PDB entry 6u12

View 6u12 on RCSB PDB site
Description: VHH R303 C33A/C102A in complex withthe LRR domain of InlB
Class: immune system
Keywords: Nanobody, VHH, Internalin, Listeria, Disulfide bond, IMMUNE SYSTEM
Deposited on 2019-08-15, released 2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-08, with a file datestamp of 2020-04-03.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: InlB
    Species: Listeria monocytogenes [TaxId:1639]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q45GD4 (16-End)
      • engineered mutation (97)
      • engineered mutation (222)
    Domains in SCOPe 2.08: d6u12a_
  • Chain 'B':
    Compound: VHH R303 C33A/C102A mutant
    Species: Camelus dromedarius [TaxId:9838]
    Database cross-references and differences (RAF-indexed):
    • PDB 6U12 (0-End)
    Domains in SCOPe 2.08: d6u12b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6u12A (A:)
mgshhhhhhenlyfqgetitvstpikqifpddafaetikdnlkkksvtdavtqnelnsid
qiiannsdiksvqgiqylpnvtklflngnkltdikplvnlknlgwlfldenkikdlsslk
dlkklkslslehngisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqis
divplagltklqnlylsknhisdlralaglknldvlelfsqealnkpin

    Sequence, based on observed residues (ATOM records): (download) 
    >6u12A (A:)
etitvstpikqifpddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqgiq
ylpnvtklflngnkltdikplvnlknlgwlfldenkikdlsslkdlkklkslslehngis
dinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnlyl
sknhisdlralaglknldvlelfsqea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6u12B (B:)
qvkleesgggsvqaggslrlscaasghtystyamgwfrqvpgkeregvarinvggsstwy
adsvrdrftisqdnakntvylqmnslkledtaiyyctlhrfantwslgtlnvwgqgtqvt
vssgseqkliseedlnhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6u12B (B:)
qvkleesgggsvqaggslrlscaasghtystyamgwfrqveregvarinvggsstwyads
vrdrftisqdnakntvylqmnslkledtaiyyctlhrfantwslgtlnvwgqgtqvtvss