PDB entry 6ty5

View 6ty5 on RCSB PDB site
Description: crystal structure of human tlr8 in complex with compound 11
Deposited on 2020-01-15, released 2020-08-12
The last revision was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 8
    Species: Homo sapiens [TaxId:9606]
    Gene: TLR8, UNQ249/PRO286
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Toll-like receptor 8
    Species: Homo sapiens [TaxId:9606]
    Gene: TLR8, UNQ249/PRO286
    Database cross-references and differences (RAF-indexed):
  • Heterogens: O0W, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ty5A (A:)
eenfsrsypcdekkqndsviaecsnrrlqevpqtvgkyvteldlsdnfithitnesfqgl
qnltkinlnhnpnvqhqngnpgiqsnglnitdgaflnlknlrelllednqlpqipsglpe
sltelsliqnniynitkegisrlinlknlylawncyfnkvcektniedgvfetltnlell
slsfnslshvppklpsslrklflsntqikyiseedfkglinltlldlsgncprcfnapfp
cvpcdggasinidrfafqnltqlrylnlsstslrkinaawfknmphlkvldlefnylvge
iasgafltmlprleildlsfnyikgsypqhinisrnfskllslralhlrgyvfqelredd
fqplmqlpnlstinlginfikqidfklfqnfsnleiiylsenrisplvkdtrqsyansss
fqrhirkrrstdfefdphsnfyhftrplikpqcaaygkaldlslnsiffigpnqfenlpd
iaclnlsansnaqvlsgtefsaiphvkyldltnnrldfdnasaltelsdlevldlsynsh
yfriagvthhlefiqnftnlkvlnlshnniytltdkynleskslvelvfsgnrldilwnd
ddnryisifkglknltrldlslnrlkhipneaflnlpasltelhindnmlkffnwtllqq
fprlelldlrgnkllfltdslsdftsslrtlllshnrishlpsgflsevsslkhldlssn
llktinksaletktttklsmlelhgnpfectcdigdfrrwmdehlnvkiprlvdvicasp
gdqrgksivslelttcvsdvteflvpr

    Sequence, based on observed residues (ATOM records):
    >6ty5A (A:)
srsypcdekkqndsviaecsnrrlqevpqtvgkyvteldlsdnfithitnesfqglqnlt
kinlnhnpnglnitdgaflnlknlrelllednqlpqipsglpesltelsliqnniynitk
egisrlinlknlylawncyfcektniedgvfetltnlellslsfnslshvppklpsslrk
lflsntqikyiseedfkglinltlldlsgncprcfnapfpcvpcdggasinidrfafqnl
tqlrylnlsstslrkinaawfknmphlkvldlefnylvgeiasgafltmlprleildlsf
nyikgsypqhinisrnfskllslralhlrgyvfqelreddfqplmqlpnlstinlginfi
kqidfklfqnfsnleiiylsenrispldphsnfyhftrplikpqcaaygkaldlslnsif
figpnqfenlpdiaclnlsansnaqvlsgtefsaiphvkyldltnnrldfdnasaltels
dlevldlsynshyfriagvthhlefiqnftnlkvlnlshnniytltkynleskslvelvf
sgnrldilwnryisifkglknltrldlslnrlkhipneaflnlpasltelhindnmlkff
nwtllqqfprlelldlrgnkllfltdslsdftsslrtlllshnrishlpsgflsvsslkh
ldlssnllktinksaletktttklsmlelhgnpfectcdigdfrrwmdehlnvkiprlvd
vicaspgdqrgksivsle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ty5B (B:)
eenfsrsypcdekkqndsviaecsnrrlqevpqtvgkyvteldlsdnfithitnesfqgl
qnltkinlnhnpnvqhqngnpgiqsnglnitdgaflnlknlrelllednqlpqipsglpe
sltelsliqnniynitkegisrlinlknlylawncyfnkvcektniedgvfetltnlell
slsfnslshvppklpsslrklflsntqikyiseedfkglinltlldlsgncprcfnapfp
cvpcdggasinidrfafqnltqlrylnlsstslrkinaawfknmphlkvldlefnylvge
iasgafltmlprleildlsfnyikgsypqhinisrnfskllslralhlrgyvfqelredd
fqplmqlpnlstinlginfikqidfklfqnfsnleiiylsenrisplvkdtrqsyansss
fqrhirkrrstdfefdphsnfyhftrplikpqcaaygkaldlslnsiffigpnqfenlpd
iaclnlsansnaqvlsgtefsaiphvkyldltnnrldfdnasaltelsdlevldlsynsh
yfriagvthhlefiqnftnlkvlnlshnniytltdkynleskslvelvfsgnrldilwnd
ddnryisifkglknltrldlslnrlkhipneaflnlpasltelhindnmlkffnwtllqq
fprlelldlrgnkllfltdslsdftsslrtlllshnrishlpsgflsevsslkhldlssn
llktinksaletktttklsmlelhgnpfectcdigdfrrwmdehlnvkiprlvdvicasp
gdqrgksivslelttcvsdvteflvpr

    Sequence, based on observed residues (ATOM records):
    >6ty5B (B:)
srsypcdekkqndsviaecsnrrlqevpqtvgkyvteldlsdnfithitnesfqglqnlt
kinlnhnpnglnitdgaflnlknlrelllednqlpqipsglpesltelsliqnniynitk
egisrlinlknlylawncycektniedgvfetltnlellslsfnslshvppklpsslrkl
flsntqikyiseedfkglinltlldlsgncprcfnapfpcvpcdggasinidrfafqnlt
qlrylnlsstslrkinaawfknmphlkvldlefnylvgeiasgafltmlprleildlsfn
yikgsypqhinisrnfskllslralhlrgyvfqelreddfqplmqlpnlstinlginfik
qidfklfqnfsnleiiylsenrisplvdphsnfyhftrplikpqcaaygkaldlslnsif
figpnqfenlpdiaclnlsansnaqvlsgtefsaiphvkyldltnnrldfdnasaltels
dlevldlsynshyfriagvthhlefiqnftnlkvlnlshnniytltkynleskslvelvf
sgnrldilwndddnryisifkglknltrldlslnrlkhipneaflnlpasltelhindnm
lkffnwtllqqfprlelldlrgnkllfltdslsdftsslrtlllshnrishlpsgflsev
sslkhldlssnllktinksaletktttklsmlelhgnpfectcdigdfrrwmdehlnvki
prlvdvicaspgdqrgksivsle