PDB entry 6tx0

View 6tx0 on RCSB PDB site
Description: crystal structure of tetrameric human d137n-samhd1 (residues 109-626) with xtp, dampnpp and mg
Deposited on 2020-01-13, released 2020-06-24
The last revision was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxynucleoside triphosphate triphosphohydrolase samhd1
    Species: Homo sapiens [TaxId:9606]
    Gene: SAMHD1, MOP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y3Z3
      • engineered mutation (30)
  • Chain 'B':
    Compound: deoxynucleoside triphosphate triphosphohydrolase samhd1
    Species: Homo sapiens [TaxId:9606]
    Gene: SAMHD1, MOP5
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y3Z3
      • engineered mutation (30)
  • Heterogens: DZ4, CZF, FE, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6tx0A (A:)
gsqihvdtmkvindpihghielhpllvriintpqfqrlryikqlgggyyvfpgashnrfe
hslgvgylagclvhalgekqpelqiserdvlcvqiaglchdlghgpfshmfdgrfiplar
pevkwtheqgsvmmfehlinsngikpvmeqyglipeedicfikeqivgplespvedslwp
ykgrpenksflyeivsnkrngidvdkwdyfardchhlgiqnnfdykrfikfarvcevdne
lricardkevgnlydmfhtrnslhrrayqhkvgniidtmitdaflkaddyieitgaggkk
yristaiddmeaytkltdnifleilystdpklkdareilkqieyrnlfkyvgetqptgqi
kikredyeslpkevasakpkvlldvklkaedfivdvinmdygmqeknpidhvsfycktap
nrairitknqvsqllpekfaeqlirvyckkvdrkslyaarqyfvqwcadrnftkpqdgdv
iaplitpqkkewndstsvqnptrlreasksrvqlfkddpm

    Sequence, based on observed residues (ATOM records):
    >6tx0A (A:)
tmkvindpihghielhpllvriintpqfqrlryikqlgggyyvfpgashnrfehslgvgy
lagclvhalgekqpelqiserdvlcvqiaglchdlghgpfshmfdgrfiplarpevkwth
eqgsvmmfehlinsngikpvmeqyglipeedicfikeqivgplwpykgrpenksflyeiv
snkrngidvdkwdyfardchhlgiqnnfdykrfikfarvcevdnelricardkevgnlyd
mfhtrnslhrrayqhkvgniidtmitdaflkaddyieitgaggkkyristaiddmeaytk
ltdnifleilystdpklkdareilkqieyrnlfkyvgetqptgqikikredyeslpkeva
sakpkvlldvklkaedfivdvinmdygmqeknpidhvsfycktapnrairitknqvsqll
pekfaeqlirvyckkvdrkslyaarqyfvqwcadrnftkpqdgdviaplitpqkkewn

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6tx0B (B:)
gsqihvdtmkvindpihghielhpllvriintpqfqrlryikqlgggyyvfpgashnrfe
hslgvgylagclvhalgekqpelqiserdvlcvqiaglchdlghgpfshmfdgrfiplar
pevkwtheqgsvmmfehlinsngikpvmeqyglipeedicfikeqivgplespvedslwp
ykgrpenksflyeivsnkrngidvdkwdyfardchhlgiqnnfdykrfikfarvcevdne
lricardkevgnlydmfhtrnslhrrayqhkvgniidtmitdaflkaddyieitgaggkk
yristaiddmeaytkltdnifleilystdpklkdareilkqieyrnlfkyvgetqptgqi
kikredyeslpkevasakpkvlldvklkaedfivdvinmdygmqeknpidhvsfycktap
nrairitknqvsqllpekfaeqlirvyckkvdrkslyaarqyfvqwcadrnftkpqdgdv
iaplitpqkkewndstsvqnptrlreasksrvqlfkddpm

    Sequence, based on observed residues (ATOM records):
    >6tx0B (B:)
tmkvindpihghielhpllvriintpqfqrlryikqlgggyyvfpgashnrfehslgvgy
lagclvhalgekqpelqiserdvlcvqiaglchdlghgpfshmfdgrfiplarpevkwth
eqgsvmmfehlinsngikpvmeqyglipeedicfikeqivgpllwpykgrpenksflyei
vsnkrngidvdkwdyfardchhlgiqnnfdykrfikfarvcevdnelricardkevgnly
dmfhtrnslhrrayqhkvgniidtmitdaflkaddyieitgaggkkyristaiddmeayt
kltdnifleilystdpklkdareilkqieyrnlfkyvgetqptgqikikredyeslpkev
asakpkvlldvklkaedfivdvinmdygmqeknpidhvsfycktapnrairitknqvsql
lpekfaeqlirvyckkvdrkslyaarqyfvqwcadrnftkpqdgdviaplitpqkkewn