PDB entry 6twb

View 6twb on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of Coagulation Factor XIa in Complex with Double Bridged Peptide F19
Class: blood clotting
Keywords: Protease, Coagulation factors, Inhibitor, Double bridged peptide, Phage display, BLOOD CLOTTING
Deposited on 2020-01-13, released 2020-05-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-13, with a file datestamp of 2020-05-08.
Experiment type: XRAY
Resolution: 2.91 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Coagulation factor XI
    Species: Homo sapiens [TaxId:9606]
    Gene: F11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03951
      • conflict (121)
      • conflict (123)
    Domains in SCOPe 2.07: d6twba1, d6twba2
  • Chain 'H':
    Compound: Coagulation factor XI
    Species: Homo sapiens [TaxId:9606]
    Gene: F11
    Database cross-references and differences (RAF-indexed):
  • Heterogens: O0T, NH4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6twbA (A:)
mddddkmdnecttkikprivggtasvrgewpwqvtlhttsptqrhlcggsiignqwilta
ahcfygvespkilrvysgilnqseikedtsffgvqeiiihdqykmaesgydiallklett
vgygdsqrpiclpskgdrnviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkry
rghkithkmicagyreggkdackgdsggplsckhnevwhlvgitswgegcaqrerpgvyt
nvveyvdwilektqavhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6twbA (A:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvgygdsqrpiclpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav

  • Chain 'H':
    No sequence available.