PDB entry 6tvr

View 6tvr on RCSB PDB site
Description: Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany
Class: viral protein
Keywords: receptor binding, fusion of virus membrane with host plasma membrane, VIRAL PROTEIN
Deposited on 2020-01-10, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 2.63 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • expression tag (0)
    Domains in SCOPe 2.08: d6tvra1, d6tvra2
  • Chain 'B':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrb_
  • Chain 'C':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • expression tag (0)
    Domains in SCOPe 2.08: d6tvrc1, d6tvrc2
  • Chain 'D':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrd_
  • Chain 'E':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • expression tag (0)
    Domains in SCOPe 2.08: d6tvre1, d6tvre2
  • Chain 'F':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrf_
  • Chain 'G':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (3-End)
      • expression tag (1-2)
      • expression tag (1)
    Domains in SCOPe 2.08: d6tvrg1, d6tvrg2
  • Chain 'H':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrh_
  • Chain 'I':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • expression tag (0)
    Domains in SCOPe 2.08: d6tvri1, d6tvri2
  • Chain 'J':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrj_
  • Chain 'K':
    Compound: hemagglutinin HA1
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • expression tag (0)
    Domains in SCOPe 2.08: d6tvrk1, d6tvrk2
  • Chain 'L':
    Compound: hemagglutinin HA2
    Species: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7)) [TaxId:1572188]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvrl_
  • Heterogens: CA, NAG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tvrA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpel

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tvrB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tvrC (C:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrC (C:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tvrD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tvrE (E:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrE (E:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpe

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6tvrF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6tvrG (G:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrG (G:)
pdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpigm
ligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftygs
sinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhps
stqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitfs
hnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcp
kyvnkkslmlatgmrnvpe

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6tvrH (H:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrH (H:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6tvrI (I:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrI (I:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvarpqvnglsgridfhwtlvqpgdkitfs
hnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcp
kyvnkkslmlatgmrnvpe

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6tvrJ (J:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrJ (J:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6tvrK (K:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrK (K:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvnglsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpe

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6tvrL (L:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvrL (L:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln