PDB entry 6tvd

View 6tvd on RCSB PDB site
Description: Crystal structure of the haemagglutinin from a H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue, 3'-SLN
Class: viral protein
Keywords: receptor binding, fusion of virus membrane with host plasma membrane, VIRAL PROTEIN
Deposited on 2020-01-09, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • conflict (220)
    Domains in SCOPe 2.08: d6tvda1, d6tvda2
  • Chain 'B':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdb_
  • Chain 'C':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdc_
  • Chain 'D':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdd_
  • Chain 'E':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvde_
  • Chain 'F':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdf_
  • Chain 'G':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0A7HR51 (2-End)
      • expression tag (0-1)
      • conflict (220)
    Domains in SCOPe 2.08: d6tvdg1, d6tvdg2
  • Chain 'H':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdh_
  • Chain 'I':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdi_
  • Chain 'J':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdj_
  • Chain 'K':
    Compound: hemagglutinin HA1
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdk_
  • Chain 'L':
    Compound: hemagglutinin HA2
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tvdl_
  • Heterogens: NAG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tvdA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdA (A:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tvdB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdB (B:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tvdC (C:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdC (C:)
dkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpigml
igtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftygss
insagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhpss
tqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitfsh
nggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpk
yvnkkslmlatgmrnvpe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tvdD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdD (D:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tvdE (E:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdE (E:)
dkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpigml
igtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftygss
insagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhpss
tqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitfsh
nggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpk
yvnkkslmlatgmrnvpe

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6tvdF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdF (F:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6tvdG (G:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdG (G:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpkyv
nkkslmlatgmrnvpe

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6tvdH (H:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdH (H:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6tvdI (I:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdI (I:)
dkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpigml
igtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftygss
insagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhpss
tqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitfsh
nggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpk
yvnkkslmlatgmrnvpe

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6tvdJ (J:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdJ (J:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6tvdK (K:)
dpdkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpig
mligtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftyg
ssinsagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhp
sstqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitf
shnggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqc
pkyvnkkslmlatgmrnvpelvqgr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdK (K:)
dkiclghhavangtivktltneqeevtnatetvestslnrlcmkgrnhkdlgnchpigml
igtpacdlhltgtwdtlierknaiaycypgatvneealrqkimesggiskintgftygss
insagttkacmrnggnsfyaelkwlvsknkgqnfpqttntyrnadtaehlimwgihhpss
tqekndlygtqslsisvgsstyknnfvpvvgarpqvngqsgridfhwtlvqpgdkitfsh
nggliapsrvskligrglgiqseapidnsceskcfwrggsintrlpfqnlsprtvgqcpk
yvnkkslmlatgmrnvpe

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6tvdL (L:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrlninpvk

    Sequence, based on observed residues (ATOM records): (download) 
    >6tvdL (L:)
glfgaiagfiengwegmvdgwygfrhqnaqgtgqaadykstqaaidqitgklnriikktn
tefesiesefseidhqignvinwtkdsitdiwtyqaellvamenqhtidmadsemlnlye
rvrkqlrqnaeedgkgcfeiyhacddscmesirnntydhsqyreeallnrln