PDB entry 6tty

View 6tty on RCSB PDB site
Description: Structure of ClpP from Staphylococcus aureus (apo, closed state)
Class: hydrolase
Keywords: caseinolytic protease, allosteric regulation, extended conformation, closed state, HYDROLASE
Deposited on 2019-12-30, released 2020-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-24.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttya_
  • Chain 'B':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyb_
  • Chain 'C':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyc_
  • Chain 'D':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyd_
  • Chain 'E':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttye_
  • Chain 'F':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A077UUA2 (0-194)
      • expression tag (195-196)
    Domains in SCOPe 2.08: d6ttyf1, d6ttyf2
  • Chain 'G':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyg_
  • Chain 'H':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyh_
  • Chain 'I':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A077UUA2 (Start-194)
      • expression tag (195-201)
    Domains in SCOPe 2.08: d6ttyi1, d6ttyi2
  • Chain 'J':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyj_
  • Chain 'K':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyk_
  • Chain 'L':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A077UUA2 (Start-194)
      • expression tag (195-198)
    Domains in SCOPe 2.08: d6ttyl1, d6ttyl2
  • Chain 'M':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttym_
  • Chain 'N':
    Compound: ATP-dependent Clp protease proteolytic subunit
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: clpP, clpP_1, clpP_2, BN1321_180012, BTN44_08670, C7P97_11805, CSC83_03355, CSC87_04280, DB727_01400, E3A28_04745, E4U00_01395, EP54_12650, EQ90_03850, ERS072840_01646, ERS140147_01605, FA040_07130, FVP29_07535, HMPREF3211_00508, M1K003_1188, NCTC10654_00875, NCTC10702_01301, NCTC5664_02933, NCTC7878_03438, NCTC7988_00802, RK64_04595, SAMEA2445518_01089
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ttyn_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ttyA (A:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyA (A:)
nliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiy
lyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevm
ihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeak
eyglidevmvp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ttyB (B:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyB (B:)
nliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiy
lyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevm
ihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeak
eyglidevmvp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ttyC (C:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyC (C:)
nliptvieteraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiylyin
spggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmihqp
lggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeakeygl
idevmvp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ttyD (D:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyD (D:)
nliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiy
lyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevm
ihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeak
eyglidevmvp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6ttyE (E:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyE (E:)
liptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiyl
yinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmi
hqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeake
yglidevmvp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6ttyF (F:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyF (F:)
mnliptvietaydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiylyins
pggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmihqpl
ggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeakeygli
devmvpetkws

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6ttyG (G:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyG (G:)
nliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiy
lyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevm
ihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeak
eyglidevmvp

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6ttyH (H:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyH (H:)
iptvieydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiylyinspggsv
tagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmihqplggaqg
qateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeakeyglidevmv
p

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6ttyI (I:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyI (I:)
iptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiyly
inspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmih
qplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeakey
glidevmvpetkwshpqfe

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6ttyJ (J:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyJ (J:)
liptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiyl
yinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmi
hqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeake
yglidevmvp

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6ttyK (K:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyK (K:)
liptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiyl
yinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmi
hqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeake
yglidevmvp

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6ttyL (L:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyL (L:)
nliptviettaydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiylyins
pggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmihqpl
ggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeakeygli
devmvpetkwshp

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >6ttyM (M:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyM (M:)
liptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiyl
yinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevmi
hqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeake
yglidevmvp

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >6ttyN (N:)
mnliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdi
ylyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaev
mihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeea
keyglidevmvpetkwshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6ttyN (N:)
nliptviettnrgeraydiysrllkdriimlgsqiddnvansivsqllflqaqdsekdiy
lyinspggsvtagfaiydtiqhikpdvqticigmaasmgsfllaagakgkrfalpnaevm
ihqplggaqgqateieiaanhilktreklnrilsertgqsiekiqkdtdrdnfltaeeak
eyglidevmvp