SCOPe 2.08: Structural Classification of Proteins

PDB entry 6ttk

View 6ttk on RCSB PDB site
Description: crystal structure of the kelch domain of human klhl12 in complex with dvl1 peptide
Deposited on 2019-12-27, released 2020-02-12
The last revision was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 2.38 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: kelch-like protein 12
Species: Homo sapiens [TaxId:9606]
Gene: KLHL12, C3IP1
Database cross-references and differences (RAF-indexed):
- Uniprot Q53G59 (Start-300)
Chain 'B':
Compound: kelch-like protein 12
Species: Homo sapiens [TaxId:9606]
Gene: KLHL12, C3IP1
Database cross-references and differences (RAF-indexed):
- Uniprot Q53G59 (Start-300)
Chain 'C':
Compound: kelch-like protein 12
Species: Homo sapiens [TaxId:9606]
Gene: KLHL12, C3IP1
Database cross-references and differences (RAF-indexed):
- Uniprot Q53G59
Chain 'D':
Compound: kelch-like protein 12
Species: Homo sapiens [TaxId:9606]
Gene: KLHL12, C3IP1
Database cross-references and differences (RAF-indexed):
- Uniprot Q53G59 (Start-300)
Chain 'E':
Compound: dvl1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6TTK
Chain 'F':
Compound: dvl1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6TTK
Chain 'G':
Compound: dvl1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6TTK
Chain 'H':
Compound: dvl1
Species: HOMO SAPIENS, synthetic [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 6TTK
Heterogens: NA, EDO, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6ttkA (A:)
smqgprtrarlganevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvs
lhdriyviggydgrsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsgg
fdgsrrhtsmerydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsveky
dphtghwtnvtpmatkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsm
ttprcyvgatvlrgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr
e

Sequence, based on observed residues (ATOM records):

>6ttkA (A:)
anevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvslhdriyviggyd
grsrlssvecldytgvwysvapmnvrrglagattlgdmiyvsggfdgsrrhtsmerydpn
idqwsmlgdmqtaregaglvvasgviyclggydglnilnsvekydphtghwtnvtpmatk
rsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsmttprcyvgatvlrgrl
yaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlre

Chain 'B':
Sequence, based on SEQRES records:

>6ttkB (B:)
smqgprtrarlganevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvs
lhdriyviggydgrsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsgg
fdgsrrhtsmerydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsveky
dphtghwtnvtpmatkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsm
ttprcyvgatvlrgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr
e

Sequence, based on observed residues (ATOM records):

>6ttkB (B:)
anevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvslhdriyviggyd
grsrlssvecldytgvwysvapmnvrrglagattlgdmiyvsggfdgsrrhtsmerydpn
idqwsmlgdmqtaregaglvvasgviyclggydglnilnsvekydphtghwtnvtpmatk
rsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsmttprcyvgatvlrgrl
yaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlre

Chain 'C':
Sequence, based on SEQRES records:

>6ttkC (C:)
smqgprtrarlganevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvs
lhdriyviggydgrsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsgg
fdgsrrhtsmerydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsveky
dphtghwtnvtpmatkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsm
ttprcyvgatvlrgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr
e

Sequence, based on observed residues (ATOM records):

>6ttkC (C:)
anevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvslhdriyviggyd
grsrlssvecldytgvwysvapmnvrrglagattlgdmiyvsggfdgsrrhtsmerydpn
idqwsmlgdmqtaregaglvvasgviyclggydglnilnsvekydphtghwtnvtpmatk
rsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsmttprcyvgatvlrgrl
yaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr

Chain 'D':
Sequence, based on SEQRES records:

>6ttkD (D:)
smqgprtrarlganevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvs
lhdriyviggydgrsrlssvecldytadedgvwysvapmnvrrglagattlgdmiyvsgg
fdgsrrhtsmerydpnidqwsmlgdmqtaregaglvvasgviyclggydglnilnsveky
dphtghwtnvtpmatkrsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsm
ttprcyvgatvlrgrlyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlr
e

Sequence, based on observed residues (ATOM records):

>6ttkD (D:)
anevllvvggfgsqqspidvvekydpktqewsflpsitrkrryvasvslhdriyviggyd
grsrlssvecldytagvwysvapmnvrrglagattlgdmiyvsggfdgsrrhtsmerydp
nidqwsmlgdmqtaregaglvvasgviyclggydglnilnsvekydphtghwtnvtpmat
krsgagvallndhiyvvggfdgtahlssveaynirtdswttvtsmttprcyvgatvlrgr
lyaiagydgnsllssiecydpiidswevvtsmgtqrcdagvcvlre

Chain 'E':
Sequence, based on SEQRES records:
```
>6ttkE (E:)
aytvvggppggppvr
```
Sequence, based on observed residues (ATOM records):
```
>6ttkE (E:)
gppggppv
```
Chain 'F':
Sequence, based on SEQRES records:
```
>6ttkF (F:)
aytvvggppggppvr
```
Sequence, based on observed residues (ATOM records):
```
>6ttkF (F:)
ggppggp
```
Chain 'G':
Sequence, based on SEQRES records:
```
>6ttkG (G:)
aytvvggppggppvr
```
Sequence, based on observed residues (ATOM records):
```
>6ttkG (G:)
gppggppv
```
Chain 'H':
Sequence, based on SEQRES records:
```
>6ttkH (H:)
aytvvggppggppvr
```
Sequence, based on observed residues (ATOM records):
```
>6ttkH (H:)
gppggppv
```