SCOPe 2.08: Structural Classification of Proteins

PDB entry 6tsh

View 6tsh on RCSB PDB site
Description: Beta-galactosidase in complex with deoxygalacto-nojirimycin
Class: sugar binding protein
Keywords: Bgal, nojirimycin, SUGAR BINDING PROTEIN
Deposited on 2019-12-20, released 2020-01-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: EM
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: beta-galactosidase
Species: Escherichia coli [TaxId:562]
Gene: lacZ
Database cross-references and differences (RAF-indexed):
- Uniprot Q8VNN2 (25-1039)
Domains in SCOPe 2.08: d6tsha1, d6tsha2, d6tsha3, d6tsha4, d6tsha5
Chain 'B':
Compound: beta-galactosidase
Species: Escherichia coli [TaxId:562]
Gene: lacZ
Database cross-references and differences (RAF-indexed):
- Uniprot Q8VNN2 (25-1039)
Domains in SCOPe 2.08: d6tshb1, d6tshb2, d6tshb3, d6tshb4, d6tshb5
Chain 'C':
Compound: beta-galactosidase
Species: Escherichia coli [TaxId:562]
Gene: lacZ
Database cross-references and differences (RAF-indexed):
- Uniprot Q8VNN2 (25-1039)
Domains in SCOPe 2.08: d6tshc1, d6tshc2, d6tshc3, d6tshc4, d6tshc5
Chain 'D':
Compound: beta-galactosidase
Species: Escherichia coli [TaxId:562]
Gene: lacZ
Database cross-references and differences (RAF-indexed):
- Uniprot Q8VNN2 (25-1039)
Domains in SCOPe 2.08: d6tshd1, d6tshd2, d6tshd3, d6tshd4, d6tshd5
Heterogens: DGJ, MG, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6tshA (A:)
mgsshhhhhhssglvprgshmledpvvlqrrdwenpgvtqlnrlaahppfaswrnseear
tdrpsqqlrslngewrfawfpapeavpeswlecdlpeadtvvvpsnwqmhgydapiytnv
typitvnppfvptenptgcysltfnvdeswlqegqtriifdgvnsafhlwcngrwvgygq
dsrlpsefdlsaflragenrlavmvlrwsdgsyledqdmwrmsgifrdvsllhkpttqis
dfhvatrfnddfsravleaevqmcgelrdylrvtvslwqgetqvasgtapfggeiiderg
gyadrvtlrlnvenpklwsaeipnlyravvelhtadgtlieaeacdvgfrevrienglll
lngkpllirgvnrhehhplhgqvmdeqtmvqdillmkqnnfnavrcshypnhplwytlcd
ryglyvvdeaniethgmvpmnrltddprwlpamservtrmvqrdrnhpsviiwslgnesg
hganhdalyrwiksvdpsrpvqyegggadttatdiicpmyarvdedqpfpavpkwsikkw
lslpgetrplilceyahamgnslggfakywqafrqyprlqggfvwdwvdqslikydengn
pwsayggdfgdtpndrqfcmnglvfadrtphpalteakhqqqffqfrlsgqtievtseyl
frhsdnellhwmvaldgkplasgevpldvapqgkqlielpelpqpesagqlwltvrvvqp
natawseaghisawqqwrlaenlsvtlpaashaiphlttsemdfcielgnkrwqfnrqsg
flsqmwigdkkqlltplrdqftrapldndigvseatridpnawverwkaaghyqaeaall
qctadtladavlittahawqhqgktlfisrktyridgsgqmaitvdvevasdtphparig
lncqlaqvaervnwlglgpqenypdrltaacfdrwdlplsdmytpyvfpsenglrcgtre
lnygphqwrgdfqfnisrysqqqlmetshrhllhaeegtwlnidgfhmgiggddswspsv
saefqlsagryhyqlvwcqk

Sequence, based on observed residues (ATOM records): (download)

>6tshA (A:)
vvlqrrdwenpgvtqlnrlaahppfaswrnseeartdrpsqqlrslngewrfawfpapea
vpeswlecdlpeadtvvvpsnwqmhgydapiytnvtypitvnppfvptenptgcysltfn
vdeswlqegqtriifdgvnsafhlwcngrwvgygqdsrlpsefdlsaflragenrlavmv
lrwsdgsyledqdmwrmsgifrdvsllhkpttqisdfhvatrfnddfsravleaevqmcg
elrdylrvtvslwqgetqvasgtapfggeiiderggyadrvtlrlnvenpklwsaeipnl
yravvelhtadgtlieaeacdvgfrevriengllllngkpllirgvnrhehhplhgqvmd
eqtmvqdillmkqnnfnavrcshypnhplwytlcdryglyvvdeaniethgmvpmnrltd
dprwlpamservtrmvqrdrnhpsviiwslgnesghganhdalyrwiksvdpsrpvqyeg
ggadttatdiicpmyarvdedqpfpavpkwsikkwlslpgetrplilceyahamgnslgg
fakywqafrqyprlqggfvwdwvdqslikydengnpwsayggdfgdtpndrqfcmnglvf
adrtphpalteakhqqqffqfrlsgqtievtseylfrhsdnellhwmvaldgkplasgev
pldvapqgkqlielpelpqpesagqlwltvrvvqpnatawseaghisawqqwrlaenlsv
tlpaashaiphlttsemdfcielgnkrwqfnrqsgflsqmwigdkkqlltplrdqftrap
ldndigvseatridpnawverwkaaghyqaeaallqctadtladavlittahawqhqgkt
lfisrktyridgsgqmaitvdvevasdtphpariglncqlaqvaervnwlglgpqenypd
rltaacfdrwdlplsdmytpyvfpsenglrcgtrelnygphqwrgdfqfnisrysqqqlm
etshrhllhaeegtwlnidgfhmgiggddswspsvsaefqlsagryhyqlvwcqk

Chain 'B':
Sequence, based on SEQRES records: (download)

>6tshB (B:)
mgsshhhhhhssglvprgshmledpvvlqrrdwenpgvtqlnrlaahppfaswrnseear
tdrpsqqlrslngewrfawfpapeavpeswlecdlpeadtvvvpsnwqmhgydapiytnv
typitvnppfvptenptgcysltfnvdeswlqegqtriifdgvnsafhlwcngrwvgygq
dsrlpsefdlsaflragenrlavmvlrwsdgsyledqdmwrmsgifrdvsllhkpttqis
dfhvatrfnddfsravleaevqmcgelrdylrvtvslwqgetqvasgtapfggeiiderg
gyadrvtlrlnvenpklwsaeipnlyravvelhtadgtlieaeacdvgfrevrienglll
lngkpllirgvnrhehhplhgqvmdeqtmvqdillmkqnnfnavrcshypnhplwytlcd
ryglyvvdeaniethgmvpmnrltddprwlpamservtrmvqrdrnhpsviiwslgnesg
hganhdalyrwiksvdpsrpvqyegggadttatdiicpmyarvdedqpfpavpkwsikkw
lslpgetrplilceyahamgnslggfakywqafrqyprlqggfvwdwvdqslikydengn
pwsayggdfgdtpndrqfcmnglvfadrtphpalteakhqqqffqfrlsgqtievtseyl
frhsdnellhwmvaldgkplasgevpldvapqgkqlielpelpqpesagqlwltvrvvqp
natawseaghisawqqwrlaenlsvtlpaashaiphlttsemdfcielgnkrwqfnrqsg
flsqmwigdkkqlltplrdqftrapldndigvseatridpnawverwkaaghyqaeaall
qctadtladavlittahawqhqgktlfisrktyridgsgqmaitvdvevasdtphparig
lncqlaqvaervnwlglgpqenypdrltaacfdrwdlplsdmytpyvfpsenglrcgtre
lnygphqwrgdfqfnisrysqqqlmetshrhllhaeegtwlnidgfhmgiggddswspsv
saefqlsagryhyqlvwcqk

Sequence, based on observed residues (ATOM records): (download)

>6tshB (B:)
vvlqrrdwenpgvtqlnrlaahppfaswrnseeartdrpsqqlrslngewrfawfpapea
vpeswlecdlpeadtvvvpsnwqmhgydapiytnvtypitvnppfvptenptgcysltfn
vdeswlqegqtriifdgvnsafhlwcngrwvgygqdsrlpsefdlsaflragenrlavmv
lrwsdgsyledqdmwrmsgifrdvsllhkpttqisdfhvatrfnddfsravleaevqmcg
elrdylrvtvslwqgetqvasgtapfggeiiderggyadrvtlrlnvenpklwsaeipnl
yravvelhtadgtlieaeacdvgfrevriengllllngkpllirgvnrhehhplhgqvmd
eqtmvqdillmkqnnfnavrcshypnhplwytlcdryglyvvdeaniethgmvpmnrltd
dprwlpamservtrmvqrdrnhpsviiwslgnesghganhdalyrwiksvdpsrpvqyeg
ggadttatdiicpmyarvdedqpfpavpkwsikkwlslpgetrplilceyahamgnslgg
fakywqafrqyprlqggfvwdwvdqslikydengnpwsayggdfgdtpndrqfcmnglvf
adrtphpalteakhqqqffqfrlsgqtievtseylfrhsdnellhwmvaldgkplasgev
pldvapqgkqlielpelpqpesagqlwltvrvvqpnatawseaghisawqqwrlaenlsv
tlpaashaiphlttsemdfcielgnkrwqfnrqsgflsqmwigdkkqlltplrdqftrap
ldndigvseatridpnawverwkaaghyqaeaallqctadtladavlittahawqhqgkt
lfisrktyridgsgqmaitvdvevasdtphpariglncqlaqvaervnwlglgpqenypd
rltaacfdrwdlplsdmytpyvfpsenglrcgtrelnygphqwrgdfqfnisrysqqqlm
etshrhllhaeegtwlnidgfhmgiggddswspsvsaefqlsagryhyqlvwcqk

Chain 'C':
Sequence, based on SEQRES records: (download)

>6tshC (C:)
mgsshhhhhhssglvprgshmledpvvlqrrdwenpgvtqlnrlaahppfaswrnseear
tdrpsqqlrslngewrfawfpapeavpeswlecdlpeadtvvvpsnwqmhgydapiytnv
typitvnppfvptenptgcysltfnvdeswlqegqtriifdgvnsafhlwcngrwvgygq
dsrlpsefdlsaflragenrlavmvlrwsdgsyledqdmwrmsgifrdvsllhkpttqis
dfhvatrfnddfsravleaevqmcgelrdylrvtvslwqgetqvasgtapfggeiiderg
gyadrvtlrlnvenpklwsaeipnlyravvelhtadgtlieaeacdvgfrevrienglll
lngkpllirgvnrhehhplhgqvmdeqtmvqdillmkqnnfnavrcshypnhplwytlcd
ryglyvvdeaniethgmvpmnrltddprwlpamservtrmvqrdrnhpsviiwslgnesg
hganhdalyrwiksvdpsrpvqyegggadttatdiicpmyarvdedqpfpavpkwsikkw
lslpgetrplilceyahamgnslggfakywqafrqyprlqggfvwdwvdqslikydengn
pwsayggdfgdtpndrqfcmnglvfadrtphpalteakhqqqffqfrlsgqtievtseyl
frhsdnellhwmvaldgkplasgevpldvapqgkqlielpelpqpesagqlwltvrvvqp
natawseaghisawqqwrlaenlsvtlpaashaiphlttsemdfcielgnkrwqfnrqsg
flsqmwigdkkqlltplrdqftrapldndigvseatridpnawverwkaaghyqaeaall
qctadtladavlittahawqhqgktlfisrktyridgsgqmaitvdvevasdtphparig
lncqlaqvaervnwlglgpqenypdrltaacfdrwdlplsdmytpyvfpsenglrcgtre
lnygphqwrgdfqfnisrysqqqlmetshrhllhaeegtwlnidgfhmgiggddswspsv
saefqlsagryhyqlvwcqk

Sequence, based on observed residues (ATOM records): (download)

>6tshC (C:)
vvlqrrdwenpgvtqlnrlaahppfaswrnseeartdrpsqqlrslngewrfawfpapea
vpeswlecdlpeadtvvvpsnwqmhgydapiytnvtypitvnppfvptenptgcysltfn
vdeswlqegqtriifdgvnsafhlwcngrwvgygqdsrlpsefdlsaflragenrlavmv
lrwsdgsyledqdmwrmsgifrdvsllhkpttqisdfhvatrfnddfsravleaevqmcg
elrdylrvtvslwqgetqvasgtapfggeiiderggyadrvtlrlnvenpklwsaeipnl
yravvelhtadgtlieaeacdvgfrevriengllllngkpllirgvnrhehhplhgqvmd
eqtmvqdillmkqnnfnavrcshypnhplwytlcdryglyvvdeaniethgmvpmnrltd
dprwlpamservtrmvqrdrnhpsviiwslgnesghganhdalyrwiksvdpsrpvqyeg
ggadttatdiicpmyarvdedqpfpavpkwsikkwlslpgetrplilceyahamgnslgg
fakywqafrqyprlqggfvwdwvdqslikydengnpwsayggdfgdtpndrqfcmnglvf
adrtphpalteakhqqqffqfrlsgqtievtseylfrhsdnellhwmvaldgkplasgev
pldvapqgkqlielpelpqpesagqlwltvrvvqpnatawseaghisawqqwrlaenlsv
tlpaashaiphlttsemdfcielgnkrwqfnrqsgflsqmwigdkkqlltplrdqftrap
ldndigvseatridpnawverwkaaghyqaeaallqctadtladavlittahawqhqgkt
lfisrktyridgsgqmaitvdvevasdtphpariglncqlaqvaervnwlglgpqenypd
rltaacfdrwdlplsdmytpyvfpsenglrcgtrelnygphqwrgdfqfnisrysqqqlm
etshrhllhaeegtwlnidgfhmgiggddswspsvsaefqlsagryhyqlvwcqk

Chain 'D':
Sequence, based on SEQRES records: (download)

>6tshD (D:)
mgsshhhhhhssglvprgshmledpvvlqrrdwenpgvtqlnrlaahppfaswrnseear
tdrpsqqlrslngewrfawfpapeavpeswlecdlpeadtvvvpsnwqmhgydapiytnv
typitvnppfvptenptgcysltfnvdeswlqegqtriifdgvnsafhlwcngrwvgygq
dsrlpsefdlsaflragenrlavmvlrwsdgsyledqdmwrmsgifrdvsllhkpttqis
dfhvatrfnddfsravleaevqmcgelrdylrvtvslwqgetqvasgtapfggeiiderg
gyadrvtlrlnvenpklwsaeipnlyravvelhtadgtlieaeacdvgfrevrienglll
lngkpllirgvnrhehhplhgqvmdeqtmvqdillmkqnnfnavrcshypnhplwytlcd
ryglyvvdeaniethgmvpmnrltddprwlpamservtrmvqrdrnhpsviiwslgnesg
hganhdalyrwiksvdpsrpvqyegggadttatdiicpmyarvdedqpfpavpkwsikkw
lslpgetrplilceyahamgnslggfakywqafrqyprlqggfvwdwvdqslikydengn
pwsayggdfgdtpndrqfcmnglvfadrtphpalteakhqqqffqfrlsgqtievtseyl
frhsdnellhwmvaldgkplasgevpldvapqgkqlielpelpqpesagqlwltvrvvqp
natawseaghisawqqwrlaenlsvtlpaashaiphlttsemdfcielgnkrwqfnrqsg
flsqmwigdkkqlltplrdqftrapldndigvseatridpnawverwkaaghyqaeaall
qctadtladavlittahawqhqgktlfisrktyridgsgqmaitvdvevasdtphparig
lncqlaqvaervnwlglgpqenypdrltaacfdrwdlplsdmytpyvfpsenglrcgtre
lnygphqwrgdfqfnisrysqqqlmetshrhllhaeegtwlnidgfhmgiggddswspsv
saefqlsagryhyqlvwcqk

Sequence, based on observed residues (ATOM records): (download)

>6tshD (D:)
vvlqrrdwenpgvtqlnrlaahppfaswrnseeartdrpsqqlrslngewrfawfpapea
vpeswlecdlpeadtvvvpsnwqmhgydapiytnvtypitvnppfvptenptgcysltfn
vdeswlqegqtriifdgvnsafhlwcngrwvgygqdsrlpsefdlsaflragenrlavmv
lrwsdgsyledqdmwrmsgifrdvsllhkpttqisdfhvatrfnddfsravleaevqmcg
elrdylrvtvslwqgetqvasgtapfggeiiderggyadrvtlrlnvenpklwsaeipnl
yravvelhtadgtlieaeacdvgfrevriengllllngkpllirgvnrhehhplhgqvmd
eqtmvqdillmkqnnfnavrcshypnhplwytlcdryglyvvdeaniethgmvpmnrltd
dprwlpamservtrmvqrdrnhpsviiwslgnesghganhdalyrwiksvdpsrpvqyeg
ggadttatdiicpmyarvdedqpfpavpkwsikkwlslpgetrplilceyahamgnslgg
fakywqafrqyprlqggfvwdwvdqslikydengnpwsayggdfgdtpndrqfcmnglvf
adrtphpalteakhqqqffqfrlsgqtievtseylfrhsdnellhwmvaldgkplasgev
pldvapqgkqlielpelpqpesagqlwltvrvvqpnatawseaghisawqqwrlaenlsv
tlpaashaiphlttsemdfcielgnkrwqfnrqsgflsqmwigdkkqlltplrdqftrap
ldndigvseatridpnawverwkaaghyqaeaallqctadtladavlittahawqhqgkt
lfisrktyridgsgqmaitvdvevasdtphpariglncqlaqvaervnwlglgpqenypd
rltaacfdrwdlplsdmytpyvfpsenglrcgtrelnygphqwrgdfqfnisrysqqqlm
etshrhllhaeegtwlnidgfhmgiggddswspsvsaefqlsagryhyqlvwcqk