PDB entry 6tp5

View 6tp5 on RCSB PDB site
Description: crystal structure of human transmembrane prolyl 4-hydroxylase
Deposited on 2019-12-12, released 2020-12-23
The last revision was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transmembrane prolyl 4-hydroxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: P4HTM, PH4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NXG6 (6-420)
      • expression tag (0-5)
      • conflict (17)
  • Chain 'B':
    Compound: Transmembrane prolyl 4-hydroxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: P4HTM, PH4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NXG6 (6-420)
      • expression tag (0-5)
      • conflict (17)
  • Heterogens: CA, FE2, OGA, TBU, GLY, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6tp5A (A:)
hhhhhhdessdpgpqhrvqgpgpeptlgpltrlegikvgherkvqlvtdrdhfirtlslk
pllfeipgfltdeecrliihlaqmkglqrsqilpteeyeeamstmqvsqldlfrlldqnr
dghlqlrevlaqtrlgngwwmtpesiqemyaaikadpdgdgvlslqefsnmdlrdfhkym
rshkaesselvrnshhtwlyqgegahhimrairqrvlrltrlspeivelseplqvvryge
gghyhahvdsgpvypeticshtklvanesvpfetscrymtvlfylnnvtgggetvfpvad
nrtydemsliqddvdlrdtrrhcdkgnlrvkpqqgtavfwynylpdgqgwvgdvddyslh
ggclvtrgtkwiannwinvdpsrarqalfqqemarlareggtdsqpewaldrayrdarve
l

    Sequence, based on observed residues (ATOM records):
    >6tp5A (A:)
tlgpltrlegikvgherkvqlvtdrdhfirtlslkpllfeipgfltdeecrliihlaqmk
glqrsqilpteeyeeqvsqldlfrlldqnrdghlqlrevlaqtrlgngwwmtpesiqemy
aaikadpdgdgvlslqefsnmdlrdfhkymrshkaesselvrnshhtwlyqgegahhimr
airqrvlrltrlspeivelseplqvvrygegghyhahvdsgpvypeticshtklvanesv
pfetscrymtvlfylnnvtgggetvfpvadnrtydemsliqddvdlrdtrrhcdkgnlrv
kpqqgtavfwynylpdgqgwvgdvddyslhggclvtrgtkwiannwinvdpsrarqalfq
qemarlareg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6tp5B (B:)
hhhhhhdessdpgpqhrvqgpgpeptlgpltrlegikvgherkvqlvtdrdhfirtlslk
pllfeipgfltdeecrliihlaqmkglqrsqilpteeyeeamstmqvsqldlfrlldqnr
dghlqlrevlaqtrlgngwwmtpesiqemyaaikadpdgdgvlslqefsnmdlrdfhkym
rshkaesselvrnshhtwlyqgegahhimrairqrvlrltrlspeivelseplqvvryge
gghyhahvdsgpvypeticshtklvanesvpfetscrymtvlfylnnvtgggetvfpvad
nrtydemsliqddvdlrdtrrhcdkgnlrvkpqqgtavfwynylpdgqgwvgdvddyslh
ggclvtrgtkwiannwinvdpsrarqalfqqemarlareggtdsqpewaldrayrdarve
l

    Sequence, based on observed residues (ATOM records):
    >6tp5B (B:)
lgpltrlegikvgherkvqlvtdrdhfirtlslkpllfeipgfltdeecrliihlaqmkg
lqrsqilptvsqldlfrlldqnrdghlqlrevlaqtrlgngwwmtpesiqemyaaikadp
dgdgvlslqefsnmdlrdfhkymrshkaesselvrnshhtwlyqgegahhimrairqrvl
rltrlspeivelseplqvvrygegghyhahvdsgpvypeticshtvpfetscrymtvlfy
lnnvtgggetvfpvadnrtydemsliqddvdlrdtrrhcdkgnlrvkpqqgtavfwynyl
pdgqgwvgdvddyslhggclvtrgtkwiannwinvdpsrarqalfqqemarlareg