PDB entry 6tlw

View 6tlw on RCSB PDB site
Description: human ck2 kinase alpha subunit in complex with the ATP-competitive inhibitor 4-bromobenzotriazole
Class: transferase
Keywords: ck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-transferase inhibitor complex, transferase
Deposited on 2019-12-03, released 2020-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68400 (0-390)
      • expression tag (391-398)
    Domains in SCOPe 2.08: d6tlwa_
  • Heterogens: NKZ, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tlwA (A:)
msgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainit
nnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntd
fkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglae
fyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnyd
qlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdf
ldkllrydhqsrltareamehpyfytvvkdqarmgsssmpggstpvssanmmsgissvpt
psplgplagspviaaanplgmpvpaaagaqqlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6tlwA (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqarm