PDB entry 6tlm
View 6tlm on RCSB PDB site
Description: ROR(gamma)t ligand binding domain in complex with allosteric ligand compound 13 (Glenmark)
Class: gene regulation
Keywords: Nuclear Receptor, Allosteric, Inverse Agonist, Inhibitor, GENE REGULATION
Deposited on
2019-12-03, released
2020-03-04
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-04-08, with a file datestamp of
2020-04-03.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: N/A
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Nuclear receptor ROR-gamma
Species: Homo sapiens [TaxId:9606]
Gene: RORC, NR1F3, RORG, RZRG
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6tlma_ - Heterogens: MJE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6tlmA (A:)
gsshhhhhhssglvprgshmaslteiehlvqsvcksyretcqlrledllrqrsnifsree
vtgyqrksmwemwercahhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvr
mcraynadnrtvffegkyggmelfralgcselissifdfshslsalhfsedeialytalv
linahrpglqekrkveqlqynlelafhhhlhkthrqsilaklppkgklrslcsqhverlq
ifqhlhpivvqaafpplykelfs
Sequence, based on observed residues (ATOM records): (download)
>6tlmA (A:)
lteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahhlte
aiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkyggme
lfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlqynl
elafhhhlhkthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpplykelf
s