PDB entry 6tl3

View 6tl3 on RCSB PDB site
Description: crystal structure of an estrogen receptor alpha 8-mer phosphopeptide in complex with 14-3-3sigma stabilized by a pyrrolidone1 derivative
Deposited on 2019-11-30, released 2020-04-29
The last revision was dated 2020-06-10, with a file datestamp of 2020-06-05.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein sigma
    Species: Homo sapiens [TaxId:9606]
    Gene: SFN, HME1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31947 (5-235)
      • expression tag (0-4)
  • Chain 'B':
    Compound: Estrogen receptor
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NJW, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6tl3A (A:)
gamgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggq
raawrvlssieqksneegseekgpevreyrekvetelqgvcdtvlglldshlikeagdae
srvfylkmkgdyyrylaevatgddkkriidsarsayqeamdiskkempptnpirlglaln
fsvfhyeianspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6tl3A (A:)
gamgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggq
raawrvlssieqksnekgpevreyrekvetelqgvcdtvlglldshlikagdaesrvfyl
kmkgdyyrylaevatgkkriidsarsayqeamdiskkempptnpirlglalnfsvfhyei
anspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6tl3B (B:)
aegfpatv

    Sequence, based on observed residues (ATOM records):
    >6tl3B (B:)
fpatv