PDB entry 6tky

View 6tky on RCSB PDB site
Description: Crystal structure of the DHR2 domain of DOCK10 in complex with CDC42
Class: signaling protein
Keywords: DOCK10 GEF CDC42 GTPase, SIGNALING PROTEIN
Deposited on 2019-11-29, released 2020-01-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-22, with a file datestamp of 2020-01-17.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dedicator of cytokinesis protein 10
    Species: Homo sapiens [TaxId:9606]
    Gene: DOCK10, KIAA0694, ZIZ3
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Dedicator of cytokinesis protein 10
    Species: Homo sapiens [TaxId:9606]
    Gene: DOCK10, KIAA0694, ZIZ3
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Cell division control protein 42 homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tkyc_
  • Chain 'D':
    Compound: Cell division control protein 42 homolog
    Species: Homo sapiens [TaxId:9606]
    Gene: CDC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tkyd_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tkyC (C:)
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaalepp
epkksrrc

    Sequence, based on observed residues (ATOM records): (download) 
    >6tkyC (C:)
qtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtagq
edydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlrd
dpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaale

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tkyD (D:)
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaalepp
epkksrrc

    Sequence, based on observed residues (ATOM records): (download) 
    >6tkyD (D:)
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaale