PDB entry 6tki

View 6tki on RCSB PDB site
Description: tsetse thrombin inhibitor in complex with human alpha-thrombin - tetragonal form at 12.7kev
Deposited on 2019-11-28, released 2020-11-04
The last revision was dated 2021-02-03, with a file datestamp of 2021-01-29.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Thrombin heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Tsetse thrombin inhibitor
    Species: Glossina morsitans morsitans, synthetic [TaxId:37546]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Thrombin light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TYS, NAG, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6tkiH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records):
    >6tkiH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsriekismlekiyihprynwrenldrdialmklkkpvafsdyihpvclpdreta
asllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfcagykpde
gkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvi
dqfge

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6tkiI (I:)
mkfftvlffllsiiylivaapgepgapidydeygdsseevggtplheipgirl

    Sequence, based on observed residues (ATOM records):
    >6tkiI (I:)
gepgapidydeyipgir

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6tkiL (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records):
    >6tkiL (L:)
eadcglrplfekksledkterellesyidg