PDB entry 6tjx

View 6tjx on RCSB PDB site
Description: cryo-em structure of typeii tau filaments extracted from the brains of individuals with corticobasal degeneration
Deposited on 2019-11-27, released 2020-02-05
The last revision was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: microtubule-associated protein tau
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6tjxA (A:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxA (A:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6tjxB (B:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxB (B:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6tjxC (C:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxC (C:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6tjxD (D:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxD (D:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6tjxE (E:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxE (E:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6tjxF (F:)
maeprqefevmedhagtyglgdrkdqggytmhqdqegdtdaglkesplqtptedgseepg
setsdakstptaedvtaplvdegapgkqaaaqphteipegttaeeagigdtpsledeaag
hvtqarmvskskdgtgsddkkakgadgktkiatprgaappgqkgqanatripaktppapk
tppssgeppksgdrsgysspgspgtpgsrsrtpslptpptrepkkvavvrtppkspssak
srlqtapvpmpdlknvkskigstenlkhqpgggkvqiinkkldlsnvqskcgskdnikhv
pgggsvqivykpvdlskvtskcgslgnihhkpgggqvevksekldfkdrvqskigsldni
thvpgggnkkiethkltfrenakaktdhgaeivykspvvsgdtsprhlsnvsstgsidmv
dspqlatladevsaslakqgl

    Sequence, based on observed residues (ATOM records):
    >6tjxF (F:)
kvqiinkkldlsnvqskcgskdnikhvpgggsvqivykpvdlskvtskcgslgnihhkpg
ggqvevksekldfkdrvqskigsldnithvpgggnkkiethkltfre