PDB entry 6tiz

View 6tiz on RCSB PDB site
Description: drosophila GDP-tubulin y222f mutant
Class: cell cycle
Keywords: microtubule, microtubule dynamics, microtule nucleation, cell cycle
Deposited on 2019-11-22, released 2021-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alphaTub84B, tubA84B, CG1913
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tiza1, d6tiza2
  • Chain 'B':
    Compound: Tubulin beta-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: betaTub56D, CG9277
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q24560 (0-End)
      • engineered mutation (221)
    Domains in SCOPe 2.08: d6tizb1, d6tizb2
  • Chain 'C':
    Compound: Tubulin alpha-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alphaTub84B, tubA84B, CG1913
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tizc1, d6tizc2
  • Chain 'D':
    Compound: Tubulin beta-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: betaTub56D, CG9277
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q24560 (0-End)
      • engineered mutation (221)
    Domains in SCOPe 2.08: d6tizd1, d6tizd2
  • Chain 'E':
    Compound: Stathmin-4
    Species: Rattus norvegicus [TaxId:10116]
    Gene: STMN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63043 (Start-142)
      • engineered mutation (11)
      • engineered mutation (17)
    Domains in SCOPe 2.08: d6tize_
  • Heterogens: GTP, MG, SO4, GOL, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tizA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdrtvgggddsfntffsetgagk
hvpravfvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvld
rirkladqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplvtyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredlaalekdyeevgmdsgdgegegaeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tizA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsgddsfntffsetgagkhvprav
fvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvldrirkla
dqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvstavvepyn
siltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdg
alnvdltefqtnlvpyprihfplvtyapvisaeyheqlsvaeitnacfepanqmvkcdpr
hgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpggdl
akvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedlaal
ekdyeevgmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tizB (B:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptfgdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqeatadedaefeeeqeaevden

    Sequence, based on observed residues (ATOM records): (download) 
    >6tizB (B:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptfgdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsaltvpeltqqmfdaknmmaacd
prhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprglkms
atfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqq
yqeatade

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tizC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdrtvgggddsfntffsetgagk
hvpravfvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvld
rirkladqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplvtyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredlaalekdyeevgmdsgdgegegaeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tizC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpgddsfntffsetgagkhvpravf
vdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvldrirklad
qctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvstavvepyns
iltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdga
lnvdltefqtnlvpyprihfplvtyapvisaekayqlsvaeitnacfepanqmvkcdprh
gkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpggdla
kvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedlaale
kdyeevgmds

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tizD (D:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptfgdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqeatadedaefeeeqeaevden

    Sequence, based on observed residues (ATOM records): (download) 
    >6tizD (D:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptfgdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsaltvpeltqqmfdaknmmaacd
prhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprglkms
atfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqq
yqeatad

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tizE (E:)
madmevielnkatsgqswevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrk
yqeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamler
lqekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tizE (E:)
dmevielnkatsgqswevilkppsfdgdpsleeiqkkleaaeerrkyqeaellkhlaekr
ehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevrkn
kelkeeasr