PDB entry 6tis

View 6tis on RCSB PDB site
Description: drosophila GDP-tubulin
Class: cell cycle
Keywords: microtubule, microtubule dynamics, microtule nucleation, cell cycle
Deposited on 2019-11-22, released 2021-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alphaTub84B, tubA84B, CG1913
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tisa1, d6tisa2
  • Chain 'B':
    Compound: Tubulin beta-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: betaTub56D, CG9277
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tisb1, d6tisb2
  • Chain 'C':
    Compound: Tubulin alpha-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: alphaTub84B, tubA84B, CG1913
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tisc1, d6tisc2
  • Chain 'D':
    Compound: Tubulin beta-1 chain
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: betaTub56D, CG9277
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6tisd1, d6tisd2
  • Chain 'E':
    Compound: Stathmin-4
    Species: Rattus norvegicus [TaxId:10116]
    Gene: STMN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63043 (1-142)
      • engineered mutation (1)
      • engineered mutation (11)
      • engineered mutation (17)
    Domains in SCOPe 2.08: d6tise_
  • Heterogens: GTP, MG, SO4, GOL, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tisA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdrtvgggddsfntffsetgagk
hvpravfvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvld
rirkladqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplvtyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredlaalekdyeevgmdsgdgegegaeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tisA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsggddsfntffsetgagkhvpra
vfvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvldrirkl
adqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvstavvepy
nsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfd
galnvdltefqtnlvpyprihfplvtyapvisaekayheqlsvaeitnacfepanqmvkc
dprhgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpg
gdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedl
aalekdyeevgmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tisB (B:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqeatadedaefeeeqeaevden

    Sequence, based on observed residues (ATOM records): (download) 
    >6tisB (B:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqaltvpeltqqmfdaknmmaa
cdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprglk
msatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvsey
qqyqeatade

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tisC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdrtvgggddsfntffsetgagk
hvpravfvdleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvld
rirkladqctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplvtyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredlaalekdyeevgmdsgdgegegaeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tisC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpddsfntffsetgagkhvpravfv
dleptvvdevrtgtyrqlfhpeqlitgkedaannyarghytigkeivdlvldrirkladq
ctglqgflifhsfgggtgsgftsllmerlsvdygkksklefaiypapqvstavvepynsi
ltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgal
nvdltefqtnlvpyprihfplvtyapvisaekeqlsvaeitnacfepanqmvkcdprhgk
ymaccmlyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyqpptvvpggdlakv
qravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedlaalekd
yeevgmds

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tisD (D:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqeatadedaefeeeqeaevden

    Sequence, based on observed residues (ATOM records): (download) 
    >6tisD (D:)
mreivhiqagqcgnqigakfweiisdehgidatgayhgdsdlqlerinvyyneasggkyv
pravlvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkeaescdclqgfqlthslgggtgsgmgtlliskireeypdrimntysvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsltmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqaltvpeltqqmfdaknmmaa
cdprhgryltvaaifrgrmsmkevdeqmlniqnknssyfvewipnnvktavcdipprglk
msatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvsey
qqyqeatad

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tisE (E:)
madmevielnkatsgqswevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrk
yqeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamler
lqekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tisE (E:)
admevielnkatsgqswevilkppsfdgdpsleeiqkkleaaeerrkyqeaellkhlaek
rehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevrk
nkelkeeasr