PDB entry 6tfi

View 6tfi on RCSB PDB site
Description: pxr in complex with thrombin inhibitor compound 17
Deposited on 2019-11-14, released 2020-11-11
The last revision was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA1, BHLHE74, SRC1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCOA1, BHLHE74, SRC1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: N6H, GOL, MPD, PO4, DMS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6tfiA (A:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgsggsggsshsslterhkilhrllqegsps

    Sequence, based on observed residues (ATOM records):
    >6tfiA (A:)
glteeqrmmirelmdaqmktfdttfshfknfrlpgvpsreeaakwsqvrkdlcslkvslq
lrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqis
llkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhymlkklq
lheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkim
amltelrsinaqhtqrllriqdihpfatplmqelfgitgssslterhkilhrllqegs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6tfiB (B:)
mkkghhhhhhgsertgtqplgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvl
ssgcelpeslqapsreeaakwsqvrkdlcslkvslqlrgedgsvwnykppadsggkeifs
llphmadmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgt
wecgrlsycledtaggfqqlllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlq
hrvvdqlqeqfaitlksyiecnrpqpahrflflkimamltelrsinaqhtqrllriqdih
pfatplmqelfgitgsggsggsshsslterhkilhrllqegsps

    Sequence, based on observed residues (ATOM records):
    >6tfiB (B:)
lgvqglteeqrmmirelmdaqmktfdttfshfknfrlpgvlsreeaakwsqvrkdlcslk
vslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpie
dqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqlllepmlkfhyml
kklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflf
lkimamltelrsinaqhtqrllriqdihpfatplmqelfgislterhkilhrllqegsp