PDB entry 6tei

View 6tei on RCSB PDB site
Description: Crystal structure of human protein kinase CK2alpha (CSNK2A1 gene product) in complex with the 2-aminothiazole-type inhibitor 17
Class: transferase
Keywords: protein kinase CK2, casein kinase 2, ATP-competitive inhibitor, 2-aminothiazole derivative, TRANSFERASE
Deposited on 2019-11-12, released 2020-07-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6teia_
  • Chain 'B':
    Compound: Casein kinase II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A1, CK2A1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6teib_
  • Heterogens: N4N, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6teiA (A:)
mgsshhhhhhsqdpmsgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklg
rgkysevfeainitnnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvs
rtpalvfehvnntdfkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidh
ehrklrlidwglaefyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmi
frkepffhghdnydqlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvh
senqhlvspealdfldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >6teiA (A:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6teiB (B:)
mgsshhhhhhsqdpmsgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklg
rgkysevfeainitnnekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvs
rtpalvfehvnntdfkqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidh
ehrklrlidwglaefyhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmi
frkepffhghdnydqlvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvh
senqhlvspealdfldkllrydhqsrltareamehpyfytvvkdqarmg

    Sequence, based on observed residues (ATOM records): (download) 
    >6teiB (B:)
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvvkdqar