PDB entry 6te5

View 6te5 on RCSB PDB site
Description: crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
Deposited on 2019-11-11, released 2020-11-18
The last revision was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 3.25 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldehyde dehydrogenase family 1 member A3
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH1A3, ALDH6
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Aldehyde dehydrogenase family 1 member A3
    Species: Homo sapiens [TaxId:9606]
    Gene: ALDH1A3, ALDH6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: N4Q, NAD, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6te5A (A:)
matangavengqpdrkppalprpirnlevkftkifinnewhesksgkkfatcnpstreqi
ceveegdkpdvdkaveaaqvafqrgspwrrldalsrgrllhqladlverdratlaaletm
dtgkpflhaffidlegcirtlryfagwadkiqgktiptddnvvcftrhepigvcgaitpw
nfpllmlvwklapalccgntmvlkpaeqtpltalylgslikeagfppgvvnivpgfgptv
gaaisshpqinkiaftgstevgklvkeaasrsnlkrvtlelggknpcivcadadldlave
cahqgvffnqgqcctaasrvfveeqvysefvrrsveyakkrpvgdpfdvkteqgpqidqk
qfdkileliesgkkegaklecggsamedkglfikptvfsevtdnmriakeeifgpvqpil
kfksieevikranstdygltaavftknldkalklasalesgtvwincynalyaqapfggf
kmsgngrelgeyalaeytevktvtiklgdknp

    Sequence, based on observed residues (ATOM records):
    >6te5A (A:)
irnlevkftkifinnewhesksgkkfatcnpstreqiceveegdkpdvdkaveaaqvafq
rgspwrrldalsrgrllhqladlverdratlaaletmdtgkpflhaffidlegcirtlry
fagwadkiqgktiptddnvvcftrhepigvcgaitpwnfpllmlvwklapalccgntmvl
kpaeqtpltalylgslikeagfppgvvnivpgfgptvgaaisshpqinkiaftgstevgk
lvkeaasrsnlkrvtlelggknpcivcadadldlavecahqgvffnqgqcctaasrvfve
eqvysefvrrsveyakkrpvgdpfdvkteqgpqidqkqfdkileliesgkkegaklecgg
samedkglfikptvfsevtdnmriakeeifgpvqpilkfksieevikranstdygltaav
ftknldkalklasalesgtvwincynalyaqapfggfkmsgngrelgeyalaeytevktv
tiklg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6te5B (B:)
matangavengqpdrkppalprpirnlevkftkifinnewhesksgkkfatcnpstreqi
ceveegdkpdvdkaveaaqvafqrgspwrrldalsrgrllhqladlverdratlaaletm
dtgkpflhaffidlegcirtlryfagwadkiqgktiptddnvvcftrhepigvcgaitpw
nfpllmlvwklapalccgntmvlkpaeqtpltalylgslikeagfppgvvnivpgfgptv
gaaisshpqinkiaftgstevgklvkeaasrsnlkrvtlelggknpcivcadadldlave
cahqgvffnqgqcctaasrvfveeqvysefvrrsveyakkrpvgdpfdvkteqgpqidqk
qfdkileliesgkkegaklecggsamedkglfikptvfsevtdnmriakeeifgpvqpil
kfksieevikranstdygltaavftknldkalklasalesgtvwincynalyaqapfggf
kmsgngrelgeyalaeytevktvtiklgdknp

    Sequence, based on observed residues (ATOM records):
    >6te5B (B:)
rnlevkftkifinnewhesksgkkfatcnpstreqiceveegdkpdvdkaveaaqvafqr
gspwrrldalsrgrllhqladlverdratlaaletmdtgkpflhaffidlegcirtlryf
agwadkiqgktiptddnvvcftrhepigvcgaitpwnfpllmlvwklapalccgntmvlk
paeqtpltalylgslikeagfppgvvnivpgfgptvgaaisshpqinkiaftgstevgkl
vkeaasrsnlkrvtlelggknpcivcadadldlavecahqgvffnqgqcctaasrvfvee
qvysefvrrsveyakkrpvgdpfdvkteqgpqidqkqfdkileliesgkkegaklecggs
amfikptvfsevtdnmriakeeifgpvqpilkfksieevikranstdygltaavftknld
kalklasalesgtvwincynalyaqapfggfkmsgngrelgeyalaeytevktvtiklg