PDB entry 6tde

View 6tde on RCSB PDB site
Description: Tubulin-inhibitor complex
Class: cell cycle
Keywords: cytoskeleton, cell division, intracellular transport, cell cycle
Deposited on 2019-11-08, released 2020-09-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-09-02, with a file datestamp of 2020-08-28.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PDB 6TDE (0-End)
    Domains in SCOPe 2.07: d6tdea1, d6tdea2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PDB 6TDE (0-End)
    Domains in SCOPe 2.07: d6tdeb1, d6tdeb2
  • Chain 'C':
    Compound: Tubulin alpha chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PDB 6TDE (0-End)
    Domains in SCOPe 2.07: d6tdec1, d6tdec2
  • Chain 'D':
    Compound: Tubulin beta chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • PDB 6TDE (0-End)
    Domains in SCOPe 2.07: d6tded1, d6tded2
  • Chain 'E':
    Compound: Stathmin-4
    Species: Rattus norvegicus [TaxId:10116]
    Gene: STMN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63043 (1-141)
      • expression tag (0)
      • engineered mutation (10)
      • engineered mutation (16)
    Domains in SCOPe 2.07: d6tdee1, d6tdee2
  • Heterogens: N3Z, SO4, GTP, MG, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6tdeA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tdeA (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsgddsfntffsetgagkhvprav
fvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkla
dqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepyn
siltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssitaslrfdg
alnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcd
prhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvvpgg
dlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedma
alekdyeevgvdsv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6tdeB (B:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmm
aacdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeeegedea

    Sequence, based on observed residues (ATOM records): (download) 
    >6tdeB (B:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqaltvpeltqqmfdsknmmaa
cdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglk
msatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvsey
qqyqdatade

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6tdeC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >6tdeC (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsgddsfntffsetgagkhvprav
fvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkla
dqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepyn
siltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssitaslrfdg
alnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcd
prhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvvpgg
dlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedma
alekdyeevgvdsv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6tdeD (D:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmm
aacdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeeegedea

    Sequence, based on observed residues (ATOM records): (download) 
    >6tdeD (D:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqaltvpeltqqmfdsknmmaa
cdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglk
msatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvsey
qqyqdatad

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6tdeE (E:)
admevielnkatsgqswevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrky
qeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerl
qekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >6tdeE (E:)
admevielnkatsgqswevilkppsfdgvppsleeiqkkleaaeerrkyqeaellkhlae
krehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevr
knkelkeeasr