PDB entry 6tbe

View 6tbe on RCSB PDB site
Description: LC3A in complex with (3R,4S,5R,6R)-5-hydroxy-6-((4-hydroxy-3-(4-hydroxy-3-isopentylbenzamido)-8-methyl-2-oxo-2H-chromen-7-yl)oxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate
Class: hydrolase
Keywords: Inhibitor, Complex, LC3A, autophagy, Hydrolase
Deposited on 2019-11-01, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Microtubule-associated proteins 1A/1B light chain 3A
  Species: Homo sapiens [TaxId:9606]
  Gene: MAP1LC3A
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9H492 (3-End)
    • expression tag (2)
  Domains in SCOPe 2.08: d6tbea1, d6tbea2
• Heterogens: NOV, EDO, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >6tbeA (A:)
  gamdrpfkqrrsfadrckevqqirdqhpskipviierykgekqlpvldktkflvpdhvnm
  selvkiirrrlqlnptqaffllvnqhsmvsvstpiadiyeqekdedgflymvyasqetf
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6tbeA (A:)
  mdrpfkqrrsfadrckevqqirdqhpskipviierykgekqlpvldktkflvpdhvnmse
  lvkiirrrlqlnptqaffllvnqhsmvsvstpiadiyeqekdedgflymvyasqet