PDB entry 6ta0

View 6ta0 on RCSB PDB site
Description: Human NAMPT in complex with nicotinic acid and phosphoribosyl pyrophosphate
Class: transferase
Keywords: NAD biosynthesis, substrate complex, TRANSFERASE
Deposited on 2019-10-29, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-18, with a file datestamp of 2020-11-13.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nicotinamide phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: NAMPT, PBEF, PBEF1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ta0a1, d6ta0a2
  • Chain 'B':
    Compound: Nicotinamide phosphoribosyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: NAMPT, PBEF, PBEF1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ta0b1, d6ta0b2
  • Heterogens: NIO, PRP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ta0A (A:)
mrgshhhhhhgsmnpaaeaefnillatdsykvthykqyppntskvysyfecrekktensk
lrkvkyeetvfyglqyilnkylkgkvvtkekiqeakdvykehfqddvfnekgwnyileky
dghlpieikavpegfviprgnvlftventdpecywltnwietilvqswypitvatnsreq
kkilakylletsgnldgleyklhdfgyrgvssqetagigasahlvnfkgtdtvaglalik
kyygtkdpvpgysvpaaehstitawgkdhekdafehivtqfssvpvsvvsdsydiynace
kiwgedlrhlivsrstqapliirpdsgnpldtvlkvleilgkkfpvtenskgykllppyl
rviqgdgvdintlqeivegmkqkmwsieniafgsgggllqkltrdllncsfkcsyvvtng
lginvfkdpvadpnkrskkgrlslhrtpagnfvtleegkgdleeygqdllhtvfkngkvt
ksysfdeirknaqlnieleaahh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ta0A (A:)
efnillatdsykvthykqyppntskvysyfecrekkyeetvfyglqyilnkylkgkvvtk
ekiqeakdvykehfqddvfnekgwnyilekydghlpieikavpegfviprgnvlftvent
dpecywltnwietilvqswypitvatnsreqkkilakylletsgnldgleyklhdfgyrg
vssqetagigasahlvnfkgtdtvaglalikkyygtkdpvpgysvpaaehstitawgkdh
ekdafehivtqfssvpvsvvsdsydiynacekiwgedlrhlivsrstqapliirpdsgnp
ldtvlkvleilgkkfpvtenskgykllppylrviqgdgvdintlqeivegmkqkmwsien
iafgsgggllqkltrdllncsfkcsyvvtnglginvfkdpvadpnkrskkgrlslhrtpa
gnfvtleegkgdleeygqdllhtvfkngkvtksysfdeirknaqlni

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ta0B (B:)
mrgshhhhhhgsmnpaaeaefnillatdsykvthykqyppntskvysyfecrekktensk
lrkvkyeetvfyglqyilnkylkgkvvtkekiqeakdvykehfqddvfnekgwnyileky
dghlpieikavpegfviprgnvlftventdpecywltnwietilvqswypitvatnsreq
kkilakylletsgnldgleyklhdfgyrgvssqetagigasahlvnfkgtdtvaglalik
kyygtkdpvpgysvpaaehstitawgkdhekdafehivtqfssvpvsvvsdsydiynace
kiwgedlrhlivsrstqapliirpdsgnpldtvlkvleilgkkfpvtenskgykllppyl
rviqgdgvdintlqeivegmkqkmwsieniafgsgggllqkltrdllncsfkcsyvvtng
lginvfkdpvadpnkrskkgrlslhrtpagnfvtleegkgdleeygqdllhtvfkngkvt
ksysfdeirknaqlnieleaahh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ta0B (B:)
efnillatdsykvthykqyppntskvysyfecrekvkyeetvfyglqyilnkylkgkvvt
kekiqeakdvykehfqddvfnekgwnyilekydghlpieikavpegfviprgnvlftven
tdpecywltnwietilvqswypitvatnsreqkkilakylletsgnldgleyklhdfgyr
gvssqetagigasahlvnfkgtdtvaglalikkyygtkdpvpgysvpaaehstitawgkd
hekdafehivtqfssvpvsvvsdsydiynacekiwgedlrhlivsrstqapliirpdsgn
pldtvlkvleilgkkfpvtenskgykllppylrviqgdgvdintlqeivegmkqkmwsie
niafgsgggllqkltrdllncsfkcsyvvtnglginvfkdpvadpnkrskkgrlslhrtp
agnfvtleegkgdleeygqdllhtvfkngkvtksysfdeirknaqlni