PDB entry 6t7p

View 6t7p on RCSB PDB site
Description: human plasmakallikrein protease domain in complex with active site directed inhibitor
Class: hydrolase
Keywords: S1 protease, serine protease, structure-based drug design, active site directed inhibitor, HYDROLASE
Deposited on 2019-10-22, released 2020-07-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Plasma kallikrein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLKB1, KLK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6t7pa_
  • Heterogens: MU8, GSH, DMS, PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6t7pA (A:)
ivggtnsswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
ilnlsditkdtpfsqikeiiihqnykvsegnhdialiklqaplnytefqkpiclpskgdt
stiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykegg
kdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqssdg
ka

    Sequence, based on observed residues (ATOM records): (download) 
    >6t7pA (A:)
ivggtnsswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
ilnlsditkdtpfsqikeiiihqnykvsegnhdialiklqaplnytefqkpiclpskgdt
stiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykegg
kdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqs