PDB entry 6t6b

View 6t6b on RCSB PDB site
Description: Crystal structure of PPARgamma in complex with compound 16 (MF27)
Class: DNA binding protein
Keywords: PPARG, peroxisome proliferator activated receptor gamma, inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, DNA BINDING PROTEIN
Deposited on 2019-10-18, released 2019-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6t6ba1, d6t6ba2
  • Heterogens: MLQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6t6bA (A:)
smqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmged
kikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllky
gvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleld
dsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmt
dlrqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records): (download) 
    >6t6bA (A:)
smqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmged
evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
ikktetdmslhpllqeiykd