PDB entry 6t65

View 6t65 on RCSB PDB site
Description: Crsytal structure of Acinetobacter baumannii FabG inhibitor complex at 2.35 A resolution
Class: biosynthetic protein
Keywords: Fatty acid biosynthesis, FabG, (3-oxoacyl-(Acyl-carrier-protein) reductase), ligand complex, FAS-II, BIOSYNTHETIC PROTEIN
Deposited on 2019-10-17, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-(acyl-carrier-protein) reductase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: fabG
    Database cross-references and differences (RAF-indexed):
    • Uniprot V5VHN7
      • engineered mutation (1)
    Domains in SCOPe 2.08: d6t65a_
  • Chain 'B':
    Compound: 3-oxoacyl-(acyl-carrier-protein) reductase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: fabG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6t65b_
  • Chain 'C':
    Compound: 3-oxoacyl-(acyl-carrier-protein) reductase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: fabG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6t65c_
  • Chain 'D':
    Compound: 3-oxoacyl-(acyl-carrier-protein) reductase
    Species: ACINETOBACTER BAUMANNII [TaxId:470]
    Gene: fabG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6t65d_
  • Heterogens: MLH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6t65A (A:)
maqerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldv
rnldeieavvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskr
vlkgmtkarfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsva
pgfiatemtdalsedirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvngg
lyma

    Sequence, based on observed residues (ATOM records): (download) 
    >6t65A (A:)
aqerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldvr
nldeieavvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskrv
lkgmtkarfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsvap
gfiatemtdalsedirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvnggl
ym

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6t65B (B:)
maqerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldv
rnldeieavvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskr
vlkgmtkarfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsva
pgfiatemtdalsedirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvngg
lyma

    Sequence, based on observed residues (ATOM records): (download) 
    >6t65B (B:)
rkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgaglaldvrnldeie
avvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskrvlkgmtk
arfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsvapgfiats
edirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvngglyma

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6t65C (C:)
maqerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldv
rnldeieavvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskr
vlkgmtkarfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsva
pgfiatemtdalsedirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvngg
lyma

    Sequence, based on observed residues (ATOM records): (download) 
    >6t65C (C:)
qerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldvrn
ldeieavvshieqnygpvlvlvnnallrmseddwddilnihlkavyrlskrvlkgmtkar
fgriinissvvahnysaakagieafsrslakemgsrqitvnsvapgfiatemkkmsdqva
lnrlgepqdianavsflasdkagyitgtvlhvngglym

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6t65D (D:)
maqerkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldv
rnldeieavvshieqnygpvlvlvnnagitkdnlllrmseddwddilnihlkavyrlskr
vlkgmtkarfgriinissvvahfanpgqanysaakagieafsrslakemgsrqitvnsva
pgfiatemtdalsedirkkmsdqvalnrlgepqdianavsflasdkagyitgtvlhvngg
lyma

    Sequence, based on observed residues (ATOM records): (download) 
    >6t65D (D:)
rkvalvtgasrgigaaiaqqliqdgyfvvgtatsesgaqkltdsfgeqgaglaldvrnld
eieavvshieqnygpvlvlvnnallrmseddwddilnihlkavyrlskrvlkgmtkarfg
riinissvvahnysaakagieafsrslakemgsrqitvnsvapgfiakmsdqvalnrlge
pqdianavsflasdkagyitgtvlhvngglyma