PDB entry 6t0h
View 6t0h on RCSB PDB site
Description: Crystal structure of CYP124 in complex with 1-alpha-hydroxy-vitamin D3
Class: oxidoreductase
Keywords: Cytochrome, P450, CYP, OXIDOREDUCTASE, 124, CYP124, vitamin, D3, vitaminD3, 1 alpha-hydroxy, 1-alpha-hydroxy, alfacalcidol, calciferol, cholecalciferol, tuberculosis, mycobacterium tuberculosis
Deposited on
2019-10-03, released
2020-10-14
The last revision prior to the SCOPe 2.08 freeze date was dated
2021-02-17, with a file datestamp of
2021-02-12.
Experiment type: XRAY
Resolution: 1.18 Å
R-factor: N/A
AEROSPACI score: 0.66
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: CYP124 in complex with inhibitor carbethoxyhexyl imidazole
Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6t0ha1, d6t0ha2 - Heterogens: M9B, HEM, GOL, PGE, MG, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6t0hA (A:)
mhhhhhhmglntaiatrvngtpppevpiadielgsldfwaldddvrdgafatlrreapis
fwptielpgfvagnghwaltkyddvfyasrhpdifssypnitindqtpelaeyfgsmivl
ddprhqrlrsivsraftpkvvarieaavrdrahrlvssmiannpdrqadlvselagplpl
qiicdmmgipkadhqrifhwtnvilgfgdpdlatdfdefmqvsadigayatalaedrrvn
hhddltsslveaevdgerlssreiasffillvvagnettrnaithgvlalsrypeqrdrw
wsdfdglaptaveeivrwaspvvymrrtltqdielrgtkmaagdkvslwycsanrdeskf
adpwtfdlarnpnphlgfggggahfclganlarreirvafdelrrqmpdvvateeparll
sqfihgiktlpvtws
Sequence, based on observed residues (ATOM records): (download)
>6t0hA (A:)
hhmglntaiatrvngtpppevpiadielgsldfwaldddvrdgafatlrreapisfwpti
elpgfvagnghwaltkyddvfyasrhpdifssypnitindqtpelaeyfgsmivlddprh
qrlrsivsraftpkvvarieaavrdrahrlvssmiannpdrqadlvselagplplqiicd
mmgipkadhqrifhwtnvilgfgdpdlatdfdefmqvsadigayatalaedrrvnhhddl
tsslveaevdgerlssreiasffillvvagnettrnaithgvlalsrypeqrdrwwsdfd
glaptaveeivrwaspvvymrrtltqdielrgtkmaagdkvslwycsanrdeskfadpwt
fdlarnpnphlgfggggahfclganlarreirvafdelrrqmpdvvateeparllsqfih
giktlpvtws