PDB entry 6t0g

View 6t0g on RCSB PDB site
Description: Crystal structure of CYP124 in complex with vitamin D3
Class: oxidoreductase
Keywords: Cytochrome, P450, CYP, OXIDOREDUCTASE, vitaminD3, D3, vitamin, 124, CYP124, cholecalciferol, calciferol, tuberculosis, mycobacterium tuberculosis
Deposited on 2019-10-03, released 2020-10-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methyl-branched lipid omega-hydroxylase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: cyp124, Rv2266, MTCY339.44c
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6t0ga_
  • Heterogens: VD3, HEM, MG, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6t0gA (A:)
mhhhhhhmglntaiatrvngtpppevpiadielgsldfwaldddvrdgafatlrreapis
fwptielpgfvagnghwaltkyddvfyasrhpdifssypnitindqtpelaeyfgsmivl
ddprhqrlrsivsraftpkvvarieaavrdrahrlvssmiannpdrqadlvselagplpl
qiicdmmgipkadhqrifhwtnvilgfgdpdlatdfdefmqvsadigayatalaedrrvn
hhddltsslveaevdgerlssreiasffillvvagnettrnaithgvlalsrypeqrdrw
wsdfdglaptaveeivrwaspvvymrrtltqdielrgtkmaagdkvslwycsanrdeskf
adpwtfdlarnpnphlgfggggahfclganlarreirvafdelrrqmpdvvateeparll
sqfihgiktlpvtws

    Sequence, based on observed residues (ATOM records): (download) 
    >6t0gA (A:)
lntaiatrvngtpppevpiadielgsldfwaldddvrdgafatlrreapisfwptielpg
fvagnghwaltkyddvfyasrhpdifssypnitindqtpelaeyfgsmivlddprhqrlr
sivsraftpkvvarieaavrdrahrlvssmiannpdrqadlvselagplplqiicdmmgi
pkadhqrifhwtnvilgfgdpdlatdfdefmqvsadigayatalaedrrvnhhddltssl
veaevdgerlssreiasffillvvagnettrnaithgvlalsrypeqrdrwwsdfdglap
taveeivrwaspvvymrrtltqdielrgtkmaagdkvslwycsanrdeskfadpwtfdla
rnpnphlgfggggahfclganlarreirvafdelrrqmpdvvateeparllsqfihgikt
lpvtws