PDB entry 6suk

View 6suk on RCSB PDB site
Description: Crystal structure of Neprilysin in complex with Omapatrilat.
Class: hydrolase
Keywords: metallopeptidase, Neural endopeptidase, Omapatrilat, HYDROLASE
Deposited on 2019-09-15, released 2020-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neprilysin
    Species: Homo sapiens [TaxId:9606]
    Gene: MME, EPN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6suka_
  • Heterogens: FT8, ZN, NAG, PEG, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sukA (A:)
yddgickssdciksaarliqnmdattepctdffkyacggwlkrnvipetssrygnfdilr
delevvlkdvlqepktedivavqkakalyrscinesaidsrggepllkllpdiygwpvat
enweqkygaswtaekaiaqlnskygkkvlinlfvgtddknsvnhvihidqprlglpsrdy
yectgiykeactayvdfmisvarlirqeerlpidenqlalemnkvmelekeianatakpe
drndpmllynkmtlaqiqnnfsleingkpfswlnftneimstvnisitneedvvvyapey
ltklkpiltkysardlqnlmswrfimdlvsslsrtykesrnafrkalygttsetatwrrc
anyvngnmenavgrlyveaafageskhvvedliaqirevfiqtlddltwmdaetkkraee
kalaikerigypddivsndnklnneylelnykedeyfeniiqnlkfsqskqlkklrekvd
kdewisgaavvnafyssgrnqivfpagilqppffsaqqsnslnyggigmvigheithgfd
dngrnfnkdgdlvdwwtqqsasnfkeqsqcmvyqygnfswdlaggqhlngintlgeniad
ngglgqayrayqnyikkngeekllpgldlnhkqlfflnfaqvwcgtyrpeyavnsiktdv
hspgnfriigtlqnsaefseafhcrknsymnpekkcrvw

    Sequence, based on observed residues (ATOM records): (download) 
    >6sukA (A:)
ddgickssdciksaarliqnmdattepctdffkyacggwlkrnvipetssrygnfdilrd
elevvlkdvlqepktedivavqkakalyrscinesaidsrggepllkllpdiygwpvate
nweqkygaswtaekaiaqlnskygkkvlinlfvgtddknsvnhvihidqprlglpsrdyy
ectgiykeactayvdfmisvarlirqeerlpidenqlalemnkvmelekeianatakped
rndpmllynkmtlaqiqnnfsleingkpfswlnftneimstvnisitneedvvvyapeyl
tklkpiltkysardlqnlmswrfimdlvsslsrtykesrnafrkalygttsetatwrrca
nyvngnmenavgrlyveaafageskhvvedliaqirevfiqtlddltwmdaetkkraeek
alaikerigypddivsndnklnneylelnykedeyfeniiqnlkfsqskqlkklrekvdk
dewisgaavvnafyssgrnqivfpagilqppffsaqqsnslnyggigmvigheithgfdd
ngrnfnkdgdlvdwwtqqsasnfkeqsqcmvyqygnfswdlaggqhlngintlgeniadn
gglgqayrayqnyikkngeekllpgldlnhkqlfflnfaqvwcgtyrpeyavnsiktdvh
spgnfriigtlqnsaefseafhcrknsymnpekkcrvw