PDB entry 6suh

View 6suh on RCSB PDB site
Description: Crystal structure of human transthyretin in complex with 3-O-methyltolcapone, a tolcapone analogue
Class: transport protein
Keywords: Amyloidosis, tetramer, binding protein, transport protein
Deposited on 2019-09-14, released 2020-08-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 1.26 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6suha_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Gene: TTR, PALB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6suhb_
  • Heterogens: LVE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6suhA (A:)
mashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainvavhvfrkaaddt
wepfasgktsesgelhgltteeefvegiykveidtksywkalgispfhehaevvftands
gprrytiaallspysysttavvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6suhA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6suhB (B:)
mashrllllclaglvfvseagptgtgeskcplmvkvldavrgspainvavhvfrkaaddt
wepfasgktsesgelhgltteeefvegiykveidtksywkalgispfhehaevvftands
gprrytiaallspysysttavvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6suhB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn