PDB entry 6sst

View 6sst on RCSB PDB site
Description: cryo-em structure of alpha-synuclein fibril polymorph 2b
Deposited on 2019-09-09, released 2019-12-18
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Alpha-synuclein
    Species: Homo sapiens [TaxId:9606]
    Gene: SNCA, NACP, PARK1
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6sstA (A:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstA (A:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6sstB (B:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstB (B:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6sstC (C:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstC (C:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6sstD (D:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstD (D:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6sstE (E:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstE (E:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6sstF (F:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstF (F:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6sstG (G:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstG (G:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6sstH (H:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstH (H:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6sstI (I:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstI (I:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6sstJ (J:)
mdvfmkglskakegvvaaaektkqgvaeaagktkegvlyvgsktkegvvhgvatvaektk
eqvtnvggavvtgvtavaqktvegagsiaaatgfvkkdqlgkneegapqegiledmpvdp
dneayempseegyqdyepea

    Sequence, based on observed residues (ATOM records):
    >6sstJ (J:)
gvvaaaektkqggvlyvgsktkegvvhgvatvaektkeqvtnvggavvtgvtavaqktve
gagsiaaatgfvk