PDB entry 6sql

View 6sql on RCSB PDB site
Description: Crystal structure of M. tuberculosis InhA in complex with NAD+ and N-(3-(aminomethyl)phenyl)-5-chloro-3-methylbenzo[b]thiophene-2-sulfonamide
Class: oxidoreductase
Keywords: InhA, NADH-dependent enoyl-[acyl-carrier-protein] reductase, OXIDOREDUCTASE
Deposited on 2019-09-04, released 2020-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-04-22, with a file datestamp of 2020-04-17.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: MYCOBACTERIUM TUBERCULOSIS H37RV [TaxId:83332]
    Gene: inhA, Rv1484, MTCY277.05
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6sqla_
  • Heterogens: LTK, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sqlA (A:)
smtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakap
lleldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskg
ihisaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvarea
gkygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpva
ktvcallsdwlpattgdiiyadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >6sqlA (A:)
glldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplle
ldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihi
saysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagky
gvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvaktv
callsdwlpattgdiiyadggahtqll