PDB entry 6sqh

View 6sqh on RCSB PDB site
Description: Crystal structure of mouse PRMT6 with partial C-terminal TEV cleavage site
Class: transferase
Keywords: SAM binding domain, arginine methylation, TRANSFERASE
Deposited on 2019-09-04, released 2020-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-30, with a file datestamp of 2020-09-25.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein arginine N-methyltransferase 6
    Species: Mus musculus [TaxId:10090]
    Gene: PRMT6, HRMT1L6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6NZB1
      • engineered mutation (314)
      • expression tag (383-384)
  • Chain 'B':
    Compound: Protein arginine N-methyltransferase 6
    Species: Mus musculus [TaxId:10090]
    Gene: PRMT6, HRMT1L6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6NZB1
      • engineered mutation (314)
    Domains in SCOPe 2.08: d6sqhb_

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6sqhB (B:)
mslskkrklesgdsggagaggegaeeenggeqeaapprprrtkserdqlyyecysdvsvh
eemiadqvrteayrlgilknwaalrgktvldvgagtgilsifcaqagarrvyaveasaiw
qqarevvrlngledrvhvlpgpvetvelpervdaivsewmgygllhesmlssvlhartkw
lkegglllpasaelfvapisdqmlewrlgfwsqvkqhygvdmscmesfatrclmghseiv
vqdlsgedvlarpqrfaqlelaragleqeleagvggrfrcscygsaplhgfavwfqvtfp
ggdsekplvlstsplhpathwkqallylnepvpveqdtdisgeitllpspdnprrlrill
rykvgdheektkdfamedgsenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6sqhB (B:)
cysdvsvheemiadqvrteayrlgilknwaalrgktvldvgagtgilsifcaqagarrvy
aveasaiwqqarevvrlngledrvhvlpgpvetvelpervdaivsewmgygllhesmlss
vlhartkwlkegglllpasaelfvapisdqmlewrlgfwsqvkqhygvdmscmesfatrc
lmghseivvqdlsgedvlarpqrfaqlelaragleqeleagvggrfrcscygsaplhgfa
vwfqvtfpggdsekplvlstsplhpathwkqallylnepvpveqdtdisgeitllpspdn
prrlrillrykvgdheektkdfam