SCOPe 2.08: Structural Classification of Proteins

PDB entry 6spi

View 6spi on RCSB PDB site
Description: a4v mutant of human sod1 with ebselen derivative 4
Class: oxidoreductase
Keywords: A4V SOD1 mutant, ebselen, ebselen derivatives, OXIDOREDUCTASE
Deposited on 2019-09-01, released 2020-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spia_
Chain 'B':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spib_
Chain 'C':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spic_
Chain 'D':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spid_
Chain 'E':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spie_
Chain 'F':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spif_
Chain 'G':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spig_
Chain 'H':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spih_
Chain 'I':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spii_
Chain 'J':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spij_
Chain 'K':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spik_
Chain 'L':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Gene: SOD1
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (Start-153)
  - engineered mutation (4)
Domains in SCOPe 2.08: d6spil_
Heterogens: LQW, ZN, SO4, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6spiA (A:)
matkvvcvlkgdgpvqgiinfeqkesngpvkvwgsikglteglhgfhvhefgdntagcts
agphfnplsrkhggpkdeerhvgdlgnvtadkdgvadvsiedsvislsgdhciigrtlvv
hekaddlgkggneestktgnagsrlacgvigiaq