PDB entry 6smp

View 6smp on RCSB PDB site
Description: AntDE:AntF (holo): type II PKS acyl-carrier protein in complex with its ketosynthase bound to the hexaketide
Class: protein binding
Keywords: Natural Product Biosynthesis, Polyketides, Minimal PKS System, Anthraquinone, Chain Elongation, Catalysis, PROTEIN BINDING
Deposited on 2019-08-22, released 2020-05-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-05, with a file datestamp of 2020-07-31.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acyl carrier protein
    Species: Photorhabdus luminescens [TaxId:29488]
    Gene: C6H68_21855
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: PKS_KS domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4191
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6smpb1, d6smpb2
  • Chain 'C':
    Compound: Ketoacyl_synth_N domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4190
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Acyl carrier protein
    Species: Photorhabdus luminescens [TaxId:29488]
    Gene: C6H68_21855
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: PKS_KS domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4191
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6smpe1, d6smpe2
  • Chain 'F':
    Compound: Ketoacyl_synth_N domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4190
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Acyl carrier protein
    Species: Photorhabdus luminescens [TaxId:29488]
    Gene: C6H68_21855
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: PKS_KS domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4191
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6smph1, d6smph2
  • Chain 'I':
    Compound: Ketoacyl_synth_N domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4190
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Acyl carrier protein
    Species: Photorhabdus luminescens [TaxId:29488]
    Gene: C6H68_21855
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: PKS_KS domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4191
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6smpk1, d6smpk2
  • Chain 'L':
    Compound: Ketoacyl_synth_N domain-containing protein
    Species: Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) [TaxId:243265]
    Gene: plu4190
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LLE, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6smpB (B:)
gsshhhhhhsgdpasmiinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvsk
yewgrerfgfksgaigqvygsdgnnkefvlkserkylqfaldaaemamqdanlrpsdidg
rrfgvaiataiadaagmeecllritkggkenihpdliksedydsfdfssaatsvakkyga
smsvsnistgcaagldalgiamehirygradimlagaseaplcplsigsfealgalssre
lenqqaatcpfslerdgfviaegcgililesyehakqrgahiyaelagyasvnnayhmtd
lpadgmamarcidmalkdaqispstvnyisahgsstaqndinesnaikfvlgesafgipi
nslksmtghalaaanaiesvalcleiekqyvhptinyqtpdpdcdldyipnqgcsypikt
alklssgfsgihsvivmravdna

    Sequence, based on observed residues (ATOM records): (download) 
    >6smpB (B:)
iinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvskyewgrerfgfksgaig
qvyfvlkserkylqfaldaaemamqdanlrpsdidgrrfgvaiataiadaagmeecllri
tkggkenihpdliksedydsfdfssaatsvakkygasmsvsnistgcaagldalgiameh
irygradimlagaseaplcplsigsfealgalssrelenqqaatcpfslerdgfviaegc
gililesyehakqrgahiyaelagyasvnnayhmtdlpadgmamarcidmalkdaqisps
tvnyisahgsstaqndinesnaikfvlgesafgipinslksmtghalaaanaiesvalcl
eiekqyvhptinyqtpdpdcdldyipnqgcsypiktalklssgfsgihsvivmravd

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6smpE (E:)
gsshhhhhhsgdpasmiinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvsk
yewgrerfgfksgaigqvygsdgnnkefvlkserkylqfaldaaemamqdanlrpsdidg
rrfgvaiataiadaagmeecllritkggkenihpdliksedydsfdfssaatsvakkyga
smsvsnistgcaagldalgiamehirygradimlagaseaplcplsigsfealgalssre
lenqqaatcpfslerdgfviaegcgililesyehakqrgahiyaelagyasvnnayhmtd
lpadgmamarcidmalkdaqispstvnyisahgsstaqndinesnaikfvlgesafgipi
nslksmtghalaaanaiesvalcleiekqyvhptinyqtpdpdcdldyipnqgcsypikt
alklssgfsgihsvivmravdna

    Sequence, based on observed residues (ATOM records): (download) 
    >6smpE (E:)
iinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvskyewgrerfgfksgaig
qvyfvlkserkylqfaldaaemamqdanlrpsdidgrrfgvaiataiadaagmeecllri
tkggkenihpdliksedydsfdfssaatsvakkygasmsvsnistgcaagldalgiameh
irygradimlagaseaplcplsigsfealgalssrelenqqaatcpfslerdgfviaegc
gililesyehakqrgahiyaelagyasvnnayhmtdlpadgmamarcidmalkdaqisps
tvnyisahgsstaqndinesnaikfvlgesafgipinslksmtghalaaanaiesvalcl
eiekqyvhptinyqtpdpdcdldyipnqgcsypiktalklssgfsgihsvivmravd

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6smpH (H:)
gsshhhhhhsgdpasmiinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvsk
yewgrerfgfksgaigqvygsdgnnkefvlkserkylqfaldaaemamqdanlrpsdidg
rrfgvaiataiadaagmeecllritkggkenihpdliksedydsfdfssaatsvakkyga
smsvsnistgcaagldalgiamehirygradimlagaseaplcplsigsfealgalssre
lenqqaatcpfslerdgfviaegcgililesyehakqrgahiyaelagyasvnnayhmtd
lpadgmamarcidmalkdaqispstvnyisahgsstaqndinesnaikfvlgesafgipi
nslksmtghalaaanaiesvalcleiekqyvhptinyqtpdpdcdldyipnqgcsypikt
alklssgfsgihsvivmravdna

    Sequence, based on observed residues (ATOM records): (download) 
    >6smpH (H:)
iinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvskyewgrerfgfksgaig
qvyerkylqfaldaaemamqdanlrpsdidgrrfgvaiataiadaagmeecllritkggk
enihpdliksedydsfdfssaatsvakkygasmsvsnistgcaagldalgiamehirygr
adimlagaseaplcplsigsfealgalssrelenqqaatcpfslerdgfviaegcgilil
esyehakqrgahiyaelagyasvnnayhmtdlpadgmamarcidmalkdaqispstvnyi
sahgsstaqndinesnaikfvlgesafgipinslksmtghalaaanaiesvalcleiekq
yvhptinyqtpdpdcdldyipnqgcsypiktalklssgfsgihsvivmravdn

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6smpK (K:)
gsshhhhhhsgdpasmiinnrnesqprrvvvtglgvvaptgvgvnefwnnihngksgvsk
yewgrerfgfksgaigqvygsdgnnkefvlkserkylqfaldaaemamqdanlrpsdidg
rrfgvaiataiadaagmeecllritkggkenihpdliksedydsfdfssaatsvakkyga
smsvsnistgcaagldalgiamehirygradimlagaseaplcplsigsfealgalssre
lenqqaatcpfslerdgfviaegcgililesyehakqrgahiyaelagyasvnnayhmtd
lpadgmamarcidmalkdaqispstvnyisahgsstaqndinesnaikfvlgesafgipi
nslksmtghalaaanaiesvalcleiekqyvhptinyqtpdpdcdldyipnqgcsypikt
alklssgfsgihsvivmravdna

    Sequence, based on observed residues (ATOM records): (download) 
    >6smpK (K:)
iinnrnqprrvvvtglgvvaptgvgvnefwnnihngksgvskyewgrerfgfksgaigqv
yrkylqfaldaaemamqdanlrpsdidgrrfgvaiataiadaagmeecllritkggkeni
hpdliksedydsfdfssaatsvakkygasmsvsnistgcaagldalgiamehirygradi
mlagaseaplcplsigsfealgalssrelenqqaatcpfslerdgfviaegcgililesy
ehakqrgahiyaelagyasvnnayhmtdlpadgmamarcidmalkdaqispstvnyisah
gsstaqndinesnaikfvlgesafgipinslksmtghalaaanaiesvalcleiekqyvh
ptinyqtpdpdcdldyipnqgcsypiktalklssgfsgihsvivmravd

  • Chain 'L':
    No sequence available.