PDB entry 6sm2

View 6sm2 on RCSB PDB site
Description: Mutant immunoglobulin light chain causing amyloidosis (Pat-1)
Class: protein fibril
Keywords: AL Amyloidosis, Antibody Folding, Protein Stability, Dynamics, protein fibril
Deposited on 2019-08-21, released 2020-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pat-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6SM2
    Domains in SCOPe 2.08: d6sm2a_
  • Chain 'B':
    Compound: Pat-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6SM2
    Domains in SCOPe 2.08: d6sm2b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sm2A (A:)
qsaltqpasvsgslgqsitisctgssndfgdynyvswyqqhpgkapklmiydvdnrpsgv
snrfsgsksgntasltisgvlaedeadyfcssytssstlyvfgsgtkvtvlg

    Sequence, based on observed residues (ATOM records): (download) 
    >6sm2A (A:)
altqpasvsgslgqsitisctgssndfgdynyvswyqqhpgkapklmiydvdnrpsgvsn
rfsgsksgntasltisgvlaedeadyfcssytssstlyvfgsgtkvtvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6sm2B (B:)
qsaltqpasvsgslgqsitisctgssndfgdynyvswyqqhpgkapklmiydvdnrpsgv
snrfsgsksgntasltisgvlaedeadyfcssytssstlyvfgsgtkvtvlg

    Sequence, based on observed residues (ATOM records): (download) 
    >6sm2B (B:)
altqpasvsgslgqsitisctgssndfgdynyvswyqqhpgkapklmiydvdnrpsgvsn
rfsgsksgntasltisgvlaedeadyfcssytssstlyvfgsgtkvtvl