PDB entry 6skp

View 6skp on RCSB PDB site
Description: OXA-10_IPM. Structural insight to the enhanced carbapenem efficiency of OXA-655 compared to OXA-10.
Class: antibiotic
Keywords: Class D beta-lactamase, crystal structures, Carbapenemases, Antibiotic resistance, antibiotic
Deposited on 2019-08-16, released 2019-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-09, with a file datestamp of 2020-09-04.
Experiment type: XRAY
Resolution: 1.89 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: blaoxa-10, blaOXA-10, oxa-10, BK373_28375, CQP61_30695, E4Z89_25540, FORC82_p097
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6skpa_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Gene: blaoxa-10, blaOXA-10, oxa-10, BK373_28375, CQP61_30695, E4Z89_25540, FORC82_p097
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6skpb_
  • Heterogens: IM2, KCX, NA, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6skpA (A:)
mktfaayviiaclsstalagsitentswnkefsaeavngvfvlckssskscatndlaras
keylpastfkipnaiigletgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvf
qqiarevgevrmqkylkkfsygnqnisggidkfwlegqlrisavnqvefleslylnklsa
skenqlivkealvteaapeylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmd
idnesklplrksiptkimesegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >6skpA (A:)
sitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiiglet
gviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkkfs
ygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaapey
lvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkimes
egiig

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6skpB (B:)
mktfaayviiaclsstalagsitentswnkefsaeavngvfvlckssskscatndlaras
keylpastfkipnaiigletgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvf
qqiarevgevrmqkylkkfsygnqnisggidkfwlegqlrisavnqvefleslylnklsa
skenqlivkealvteaapeylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmd
idnesklplrksiptkimesegiigg

    Sequence, based on observed residues (ATOM records): (download) 
    >6skpB (B:)
gsitentswnkefsaeavngvfvlckssskscatndlaraskeylpastfkipnaiigle
tgviknehqvfkwdgkpramkqwerdltlrgaiqvsavpvfqqiarevgevrmqkylkkf
sygnqnisggidkfwlegqlrisavnqvefleslylnklsaskenqlivkealvteaape
ylvhsktgfsgvgtesnpgvawwvgwveketevyffafnmdidnesklplrksiptkime
segiig