PDB entry 6siq

View 6siq on RCSB PDB site
Description: fragment az-012 binding at the p53pt387/14-3-3 sigma interface
Deposited on 2019-08-10, released 2020-06-17
The last revision was dated 2020-07-22, with a file datestamp of 2020-07-17.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein sigma
    Species: Homo sapiens [TaxId:9606]
    Gene: SFN, HME1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P31947 (5-235)
      • expression tag (0-4)
  • Chain 'P':
    Compound: Cellular tumor antigen p53
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LF5, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6siqA (A:)
gamgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggq
raawrvlssieqksneegseekgpevreyrekvetelqgvcdtvlglldshlikeagdae
srvfylkmkgdyyrylaevatgddkkriidsarsayqeamdiskkempptnpirlglaln
fsvfhyeianspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

    Sequence, based on observed residues (ATOM records):
    >6siqA (A:)
gamgsmerasliqkaklaeqaeryedmaafmkgavekgeelsceernllsvayknvvggq
raawrvlssieqksnpevreyrekvetelqgvcdtvlglldshlikeagdaesrvfylkm
kgdyyrylaevatgddkkriidsarsayqeamdiskkempptnpirlglalnfsvfhyei
anspeeaislakttfdeamadlhtlsedsykdstlimqllrdnltlwt

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6siqP (P:)
klmfktegpdsd

    Sequence, based on observed residues (ATOM records):
    >6siqP (P:)
mfktegpdsd