PDB entry 6shv

View 6shv on RCSB PDB site
Description: T. cruzi FPPS in complex with 5-(4-fluorophenoxy)pyridin-2-amine
Class: transferase
Keywords: farnesyl diphosphate synthase, sterol biosynthesis, farnesyl pyrophosphate, homodimer, TRANSFERASE
Deposited on 2019-08-08, released 2020-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-08-26, with a file datestamp of 2020-08-21.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Farnesyl Diphosphate Synthase
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6shva_
  • Heterogens: LDW, ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6shvA (A:)
gpmasmerflsvydevqaflldqlqskyeidpnrarylrimmdttclggkyfrgmtvvnv
aegflavtqhdeatkerilhdacvggwmieflqahylveddimdgsvmrrgkpcwyrfpg
vttqcaindgiilkswtqimawhyfadrpflkdllclfqkvdyatavgqmydvtsmcdsn
kldpevaqpmttdfaeftpaiykrivkykttfytyllplvmgllvseaaasvemnlverv
ahligeyfqvqddvmdcftppeqlgkvgtdiedakcswlavtflgkanaaqvaefkanyg
ekdpakvavvkrlyskanlqadfaayeaevvreveslieqlkvksptfaesvavvwekth
krkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6shvA (A:)
asmerflsvydevqaflldqlqskyeidpnrarylrimmdttclggkyfrgmtvvnvaeg
flavtqhdeatkerilhdacvggwmieflqahylveddimdgsvmrrgkpcwyrfpgvtt
qcaindgiilkswtqimawhyfadrpflkdllclfqkvdyatavgqmydvtsmcdsnkld
pevaqpmttdfaeftpaiykrivkykttfytyllplvmgllvseaaasvemnlvervahl
igeyfqvqddvmdcftppgtdiedakcswlavtflgkanaaqvaefkanygekdpakvav
vkrlyskanlqadfaayeaevvreveslieqlkvksptfaesvavvwekth