PDB entry 6seg

View 6seg on RCSB PDB site
Description: class1: cenp-a nucleosome in complex with cenp-c central region
Deposited on 2019-07-30, released 2019-08-14
The last revision was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: EM
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone H2A type 2-A
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST2H2AA3, H2AFO, HIST2H2AA, HIST2H2AA4
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone H2B type 1-C/E/F/G/I
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Histone H3-like centromeric protein A
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPA
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Histone H2A type 2-A
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST2H2AA3, H2AFO, HIST2H2AA, HIST2H2AA4
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Histone H2B type 1-C/E/F/G/I
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA (145-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'J':
    Compound: DNA (145-mer)
    Species: synthetic construct, synthetic [TaxId:32630]

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6segA (A:)
mgprrrsrkpeaprrrspsptptpgpsrrgpslgasshqhsrrrqgwlkeirklqksthl
lirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhagrvt
lfpkdvqlarrirgleeglg

    Sequence, based on observed residues (ATOM records):
    >6segA (A:)
qgwlkeirklqksthllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvh
lfedaylltlhagrvtlfpkdvqlarrirgleegl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6segB (B:)
msgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >6segB (B:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygfgg

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6segC (C:)
msgrgkqggkarakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleylt
aeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllpkk
teshhkakgk

    Sequence, based on observed residues (ATOM records):
    >6segC (C:)
srssraglqfpvgrvhrllrkgnyaervgagapvymaavleyltaeilelagnaardnkk
triiprhlqlairndeelnkllgkvtiaqggvlpni

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6segD (D:)
mpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysvyvykvlkqvhpdtgisskam
gimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavt
kytssk

    Sequence, based on observed residues (ATOM records):
    >6segD (D:)
rkesysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsr
eiqtavrlllpgelakhavsegtkavtkytss

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6segE (E:)
mgprrrsrkpeaprrrspsptptpgpsrrgpslgasshqhsrrrqgwlkeirklqksthl
lirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvhlfedaylltlhagrvt
lfpkdvqlarrirgleeglg

    Sequence, based on observed residues (ATOM records):
    >6segE (E:)
qgwlkeirklqksthllirklpfsrlareicvkftrgvdfnwqaqallalqeaaeaflvh
lfedaylltlhagrvtlfpkdvqlarrirgleegl

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6segF (F:)
msgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >6segF (F:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygfgg

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6segG (G:)
msgrgkqggkarakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleylt
aeilelagnaardnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqavllpkk
teshhkakgk

    Sequence, based on observed residues (ATOM records):
    >6segG (G:)
rakaksrssraglqfpvgrvhrllrkgnyaervgagapvymaavleyltaeilelagnaa
rdnkktriiprhlqlairndeelnkllgkvtiaqggvlpniqav

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6segH (H:)
mpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysvyvykvlkqvhpdtgisskam
gimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavt
kytssk

    Sequence, based on observed residues (ATOM records):
    >6segH (H:)
esysvyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsrei
qtavrlllpgelakhavsegtkavtkytss

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.