PDB entry 6sdz

View 6sdz on RCSB PDB site
Description: transthyritin derived amyloid fibril from patient with hereditary V30M ATTR amyloidosis
Class: protein fibril
Keywords: amyloid fibril, systemic ATTR amyloidosis, ex vivo, misfolding, patient tissue, transthyritin, PROTEIN FIBRIL
Deposited on 2019-07-29, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: EM
Resolution: 2.97 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdza_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzb_
  • Chain 'C':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzc_
  • Chain 'D':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzd_
  • Chain 'E':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdze_
  • Chain 'F':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzf_
  • Chain 'G':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzg_
  • Chain 'H':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzh_
  • Chain 'I':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzi_
  • Chain 'J':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzj_
  • Chain 'K':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sdzk_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sdzA (A:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzA (A:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6sdzB (B:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzB (B:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6sdzC (C:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzC (C:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6sdzD (D:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzD (D:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6sdzE (E:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzE (E:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6sdzF (F:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzF (F:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6sdzG (G:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzG (G:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6sdzH (H:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzH (H:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6sdzI (I:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzI (I:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6sdzJ (J:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzJ (J:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6sdzK (K:)
gptgtgeskcplmvkvldavrgspainvamhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystta
vvtnpke

    Sequence, based on observed residues (ATOM records): (download) 
    >6sdzK (K:)
plmvkvldavrgspainvamhvfrkgltteeefvegiykveidtksywkalgispfheha
evvftandsgprrytiaallspysysttavvt