PDB entry 6sdt
View 6sdt on RCSB PDB site
Description: human carbonic anhydrase vii in complex with a sulfonamide inhibitor
Class: lyase
Keywords: carbonic anhydrase vii, zinc enzyme, inhibitor, sulfonamide, lyase
Deposited on
2019-07-29, released
2020-06-10
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-06-10, with a file datestamp of
2020-06-05.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Carbonic anhydrase 7
Species: Homo sapiens [TaxId:9606]
Gene: CA7
Database cross-references and differences (RAF-indexed):
- Uniprot P43166 (Start-265)
- engineered mutation (186)
- engineered mutation (220)
Domains in SCOPe 2.08: d6sdta_ - Heterogens: L8N, ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6sdtA (A:)
mgmtghhgwgygqddgpshwhklypiaqgdrqspiniissqavyspslqplelsyeacms
lsitnnghsvqvdfndsddrtvvtggplegpyrlkqfhfhwgkkhdvgsehtvdgksfps
elhlvhwnakkystfgeaasapdglavvgvfletgdehpsmnrltdalymvrfkgtkaqf
scfnpksllpasrhywtypgslttpplsesvtwivlrepisiserqmgkfrsllftsedd
erihmvnnfrppqplkgrvvkasfralehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6sdtA (A:)
gwgygqddgpshwhklypiaqgdrqspiniissqavyspslqplelsyeacmslsitnng
hsvqvdfndsddrtvvtggplegpyrlkqfhfhwgkkhdvgsehtvdgksfpselhlvhw
nakkystfgeaasapdglavvgvfletgdehpsmnrltdalymvrfkgtkaqfscfnpks
llpasrhywtypgslttpplsesvtwivlrepisiserqmgkfrsllftsedderihmvn
nfrppqplkgrvvkasfra