PDB entry 6sbo

View 6sbo on RCSB PDB site
Description: Estrogen receptor mutant L536S
Class: transcription
Keywords: receptor, TRANSCRIPTION
Deposited on 2019-07-22, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered mutation (241)
    Domains in SCOPe 2.08: d6sboa_
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372
      • engineered mutation (241)
    Domains in SCOPe 2.08: d6sbob_
  • Heterogens: L5B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sboA (A:)
gamikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrel
vhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnq
gkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdh
ihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvv
psydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >6sboA (A:)
lalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdlt
lhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllat
ssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemldahrlh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6sboB (B:)
gamikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrel
vhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnq
gkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdh
ihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvv
psydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >6sboB (B:)
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlih
lmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemldahr
lh