PDB entry 6sbi

View 6sbi on RCSB PDB site
Description: X-ray structure of murine Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) in complex with inhibitor oxalate
Class: hydrolase
Keywords: Oxalate binding, TCA cycle, mitochondria, HYDROLASE
Deposited on 2019-07-21, released 2020-03-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-25, with a file datestamp of 2020-03-20.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acylpyruvase FAHD1, mitochondrial
    Species: Mus musculus [TaxId:10090]
    Gene: Fahd1, MNCb-4134
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sbia_
  • Chain 'B':
    Compound: Acylpyruvase FAHD1, mitochondrial
    Species: Mus musculus [TaxId:10090]
    Gene: Fahd1, MNCb-4134
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sbib_
  • Chain 'C':
    Compound: Acylpyruvase FAHD1, mitochondrial
    Species: Mus musculus [TaxId:10090]
    Gene: Fahd1, MNCb-4134
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sbic_
  • Chain 'D':
    Compound: Acylpyruvase FAHD1, mitochondrial
    Species: Mus musculus [TaxId:10090]
    Gene: Fahd1, MNCb-4134
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sbid_
  • Heterogens: MG, OXL, K, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6sbiA (A:)
    mhhhhhhssglvprgsgmketaaakferqhmdspdlgtmtqsctmastkplsrfwewgkn
    ivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycrnlhhevelgvllg
    krgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksftsscpvsafvpkek
    ipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegdliltgtpkgvgpi
    kendeieagidgvvsmrfkvkrsey
    

    Sequence, based on observed residues (ATOM records): (download)
    >6sbiA (A:)
    tkplsrfwewgknivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycr
    nlhhevelgvllgkrgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksft
    sscpvsafvpkekipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegd
    liltgtpkgvgpikendeieagidgvvsmrfkvkrs
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6sbiB (B:)
    mhhhhhhssglvprgsgmketaaakferqhmdspdlgtmtqsctmastkplsrfwewgkn
    ivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycrnlhhevelgvllg
    krgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksftsscpvsafvpkek
    ipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegdliltgtpkgvgpi
    kendeieagidgvvsmrfkvkrsey
    

    Sequence, based on observed residues (ATOM records): (download)
    >6sbiB (B:)
    tkplsrfwewgknivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycr
    nlhhevelgvllgkrgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksft
    sscpvsafvpkekipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegd
    liltgtpkgvgpikendeieagidgvvsmrfkvkrs
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6sbiC (C:)
    mhhhhhhssglvprgsgmketaaakferqhmdspdlgtmtqsctmastkplsrfwewgkn
    ivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycrnlhhevelgvllg
    krgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksftsscpvsafvpkek
    ipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegdliltgtpkgvgpi
    kendeieagidgvvsmrfkvkrsey
    

    Sequence, based on observed residues (ATOM records): (download)
    >6sbiC (C:)
    plsrfwewgknivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycrnl
    hhevelgvllgkrgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksftss
    cpvsafvpkekipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegdli
    ltgtpkgvgpikendeieagidgvvsmrfkvkrs
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6sbiD (D:)
    mhhhhhhssglvprgsgmketaaakferqhmdspdlgtmtqsctmastkplsrfwewgkn
    ivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycrnlhhevelgvllg
    krgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksftsscpvsafvpkek
    ipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegdliltgtpkgvgpi
    kendeieagidgvvsmrfkvkrsey
    

    Sequence, based on observed residues (ATOM records): (download)
    >6sbiD (D:)
    tkplsrfwewgknivcvgrnyadhvkemrstvlsepvlflkpstayapegspvlmpaycr
    nlhhevelgvllgkrgeaipeaaamdyvagyalcldmtardvqeeckkkglpwtlaksft
    sscpvsafvpkekipdphalrlwlkvngelrqegktssmifsipyiisyvskiitleegd
    liltgtpkgvgpikendeieagidgvvsmrfkvkrs