PDB entry 6sa3

View 6sa3 on RCSB PDB site
Description: Crystal Structure of BRD4(1) bound to inhibitor BUX4 (13)
Class: transcription
Keywords: BRD4, BRD4(1), INHIBITOR, BROMODOMAIN, EPIGENETIC READER PROTEIN, ACETYLATED, LYSINE, HISTONE TAIL, PROTEIN BINDING-INHIBITOR COMPLEX, BUX4, fragment, transcription
Deposited on 2019-07-16, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-06, with a file datestamp of 2021-01-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sa3a_
  • Heterogens: L2N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sa3A (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

    Sequence, based on observed residues (ATOM records): (download) 
    >6sa3A (A:)
rqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiiktpmdmgtikkrlenn
yywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkinelpt