PDB entry 6sa2

View 6sa2 on RCSB PDB site
Description: Crystal Structure of BRD4(1) bound to inhibitor BUX3 (10)
Class: transcription
Keywords: BRD4, BRD4(1), INHIBITOR, BROMODOMAIN, EPIGENETIC READER PROTEIN, ACETYLATED, LYSINE, HISTONE TAIL, PROTEIN BINDING-INHIBITOR COMPLEX, BUX3, fragment, transcription
Deposited on 2019-07-16, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-06, with a file datestamp of 2021-01-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 4
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD4, HUNK1
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60885 (2-126)
    • expression tag (0-1)
  Domains in SCOPe 2.08: d6sa2a1, d6sa2a2
• Heterogens: L25, BU3, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6sa2A (A:)
  smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
  ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
  nelptee