PDB entry 6s8s

View 6s8s on RCSB PDB site
Description: Extended structure of the human DDX6 C-terminal domain in complex with an EDC3 FDF peptide
Class: RNA binding protein
Keywords: Translational control, mRNA decay, miRNA, RNA binding protein
Deposited on 2019-07-10, released 2019-09-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-09, with a file datestamp of 2019-10-04.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: probable ATP-dependent RNA helicase ddx6
    Species: Homo sapiens [TaxId:9606]
    Gene: DDX6, HLR2, RCK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s8sa_
  • Chain 'B':
    Compound: enhancer of mRNA-decapping protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: EDC3, LSM16, YJDC, YJEFN2, PP844
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96F86 (7-End)
      • expression tag (5-6)
  • Chain 'C':
    Compound: probable ATP-dependent RNA helicase ddx6
    Species: Homo sapiens [TaxId:9606]
    Gene: DDX6, HLR2, RCK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s8sc_
  • Chain 'D':
    Compound: enhancer of mRNA-decapping protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: EDC3, LSM16, YJDC, YJEFN2, PP844
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96F86 (7-End)
      • expression tag (5-6)
  • Heterogens: PO4, CXS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6s8sA (A:)
gpqdpyeinlmeeltlkgvtqyyayvterqkvhclntlfsrlqinqsiifcnssqrvell
akkisqlgyscfyihakmrqehrnrvfhdfrnglcrnlvctdlftrgidiqavnvvinfd
fpklaetylhrigrsgrfghlglainlityddrfnlksieeqlgteikpipsnidkslyv
aeyhsepvedekp

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8sA (A:)
kgvtqyyayvterqkvhclntlfsrlqinqsiifcnssqrvellakkisqlgyscfyiha
kmrqehrnrvfhdfrnglcrnlvctdlftrgidiqavnvvinfdfpklaetylhrigrsg
rfghlglainlityddrfnlksieeqlgteikpipsnidkslyvaeyh

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6s8sC (C:)
gpqdpyeinlmeeltlkgvtqyyayvterqkvhclntlfsrlqinqsiifcnssqrvell
akkisqlgyscfyihakmrqehrnrvfhdfrnglcrnlvctdlftrgidiqavnvvinfd
fpklaetylhrigrsgrfghlglainlityddrfnlksieeqlgteikpipsnidkslyv
aeyhsepvedekp

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8sC (C:)
kgvtqyyayvterqkvhclntlfsrlqinqsiifcnssqrvellakkisqlgyscfyiha
kmrqehrnrvfhdfrnglcrnlvctdlftrgidiqavnvvinfdfpklaetylhrigrsg
rfghlglainlityddrfnlksieeqlgteikpipsnidkslyvaeyhsepve

  • Chain 'D':
    No sequence available.