PDB entry 6s8i

View 6s8i on RCSB PDB site
Description: Structure of ZEBOV GP in complex with 3T0265 antibody
Class: viral protein
Keywords: Ebola, glycoprotein, antibodies, VIRAL PROTEIN
Deposited on 2019-07-10, released 2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: EM
Resolution: 2.99 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enveloped Glycoprotein 1
    Species: Ebola virus [TaxId:1570291]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
  • Chain 'B':
    Compound: Envelope glycoprotein
    Species: Ebola virus [TaxId:1570291]
    Gene: GP, DF49_53415gpGP, DF49_53416gpGP, DF49_53417gpGP, DF49_53418gpGP, DF49_53419gpGP, DF49_53420gpGP, DF49_53421gpGP, DF49_53422gpGP, DF49_53423gpGP, DF49_53424gpGP, DF49_53425gpGP, DF49_53426gpGP
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Enveloped Glycoprotein 1
    Species: Ebola virus [TaxId:1570291]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
  • Chain 'D':
    Compound: Envelope glycoprotein
    Species: Ebola virus [TaxId:1570291]
    Gene: GP, DF49_53415gpGP, DF49_53416gpGP, DF49_53417gpGP, DF49_53418gpGP, DF49_53419gpGP, DF49_53420gpGP, DF49_53421gpGP, DF49_53422gpGP, DF49_53423gpGP, DF49_53424gpGP, DF49_53425gpGP, DF49_53426gpGP
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Enveloped Glycoprotein 1
    Species: Ebola virus [TaxId:1570291]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
  • Chain 'F':
    Compound: Envelope glycoprotein
    Species: Ebola virus [TaxId:1570291]
    Gene: GP, DF49_53415gpGP, DF49_53416gpGP, DF49_53417gpGP, DF49_53418gpGP, DF49_53419gpGP, DF49_53420gpGP, DF49_53421gpGP, DF49_53422gpGP, DF49_53423gpGP, DF49_53424gpGP, DF49_53425gpGP, DF49_53426gpGP
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8ih_
  • Chain 'L':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8il1
  • Chain 'O':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8io1
  • Chain 'P':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8ip_
  • Chain 'U':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8iu1
  • Chain 'Y':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6S8I
    Domains in SCOPe 2.08: d6s8iy_

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6s8iH (H:)
evqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggat
eyaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvssgst
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iH (H:)
vqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggate
yaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvss

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6s8iL (L:)
qsvltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagv
pdrfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltvlgqpkaaps
vtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaa
ssylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iL (L:)
svltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagvp
drfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltv

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >6s8iO (O:)
qsvltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagv
pdrfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltvlgqpkaaps
vtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaa
ssylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iO (O:)
svltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagvp
drfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltv

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >6s8iP (P:)
evqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggat
eyaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvssgst
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iP (P:)
vqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggate
yaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvss

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >6s8iU (U:)
qsvltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagv
pdrfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltvlgqpkaaps
vtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaa
ssylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iU (U:)
svltqppsvsgapgqrvaisctgsysnigagydvhwyqqfpgaapklliyaytnrpagvp
drfsgsksgssaslvisglqaddeadyycqsydarlrdgevfgggtkltv

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >6s8iY (Y:)
evqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggat
eyaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvssgst
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >6s8iY (Y:)
vqlvesggnlakpggslrlscaasgftfsdawmtwvrqapgkglewvgriksnadggate
yaapvrgrftisrddsrsslflqmnslktedtavyycltppprrywgqgilvtvss