PDB entry 6s7q

View 6s7q on RCSB PDB site
Description: Crystal structure of ergothioneine degrading enzyme Ergothionase from Treponema denticola in complex with desmethyl-ergothioneine sulfonic acid
Class: lyase
Keywords: ergothioneine degrading enzyme, TdETL, trimethlyammonium lyase, LYASE, ergothioneine
Deposited on 2019-07-05, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qa_
  • Chain 'B':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qb_
  • Chain 'C':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qc_
  • Chain 'D':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qd_
  • Chain 'E':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qe_
  • Chain 'F':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qf_
  • Chain 'G':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qg_
  • Chain 'H':
    Compound: ergothionase
    Species: Treponema denticola [TaxId:158]
    Gene: HMPREF9733_00339
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6s7qh_
  • Heterogens: KZ5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qA (A:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qB (B:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qC (C:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qD (D:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qE (E:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qF (F:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qG (G:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6s7qH (H:)
daliltgkplsledvysvaynnrqvkisddaeervkkarqilfdmaaegkpvyglnrgvg
wnkdkefdedffatynrnllnshclgvkpyhpdeqvrailllrlnkaltghtgisaellh
hyrdflnygihpripmrssigegdittlshiglafigeedvsfngeimnskkamekaglk
paklgpkdglsivscnaqgeamtaivlkeiedlvymsnlifclsleglngvvqslredvn
avrgikgqikaaemcreflkgsflydpdperalqdplsfrcahsvngtmydamdyvreql
lttmnttddnpciiidehssfvsanfeitslaigvemlatalshlsktscyrmikladps
ftklnrfltpqdvktiafgtiqktftmldtqnrglanpssmdfyslagtiedhasnlpla
cykifqmldniryiigieamhaaqaidlrgnkklgegtkkayslirevlpfynedrnisr
dietmyefikskkllni